Role of the protein in the DNA sequence specificity of the cleavage site stabilized by the camptothecin topoisomerase IB inhibitor: a metadynamics study

by Coletta, Andrea, Desideri, Alessandro
Published 2013

Solvent Dependency of the UV-Vis Spectrum of Indenoisoquinolines: Role of Keto-Oxygens as Polarity Interaction Probes

by Coletta, Andrea, Castelli, Silvia, Chillemi, Giovanni, Sanna, Nico, Cushman, Mark, Pommier, Yves, Desideri, Alessandro
Published 2013

Binding of an Indenoisoquinoline to the Topoisomerase-DNA Complex Induces Reduction of Linker Mobility and Strengthening of Protein-DNA Interaction

by Mancini, Giordano, D’Annessa, Ilda, Coletta, Andrea, Chillemi, Giovanni, Pommier, Yves, Cushman, Mark, Desideri, Alessandro
Published 2012

Characterization of the differences in the cyclopiazonic acid binding mode to mammalian and P. Falciparum Ca2+ pumps: A computational study

by Di Marino, Daniele, D'Annessa, Ilda, Coletta, Andrea, Via, Allegra, Tramontano, Anna
Published 2015

Simulations of DNA topoisomerase 1B bound to supercoiled DNA reveal changes in the flexibility pattern of the enzyme and a secondary protein–DNA binding site

by D'Annessa, Ilda, Coletta, Andrea, Sutthibutpong, Thana, Mitchell, Jonathan, Chillemi, Giovanni, Harris, Sarah, Desideri, Alessandro
Published 2014

A small organic compound enhances the religation reaction of human topoisomerase I and identifies crucial elements for the religation mechanism

by Arnò, Barbara, Coletta, Andrea, Tesauro, Cinzia, Zuccaro, Laura, Fiorani, Paola, Lentini, Sara, Galloni, Pierluca, Conte, Valeria, Floris, Barbara, Desideri, Alessandro
Published 2013

Isoniazid Inhibits the Heme-Based Reactivity of Mycobacterium tuberculosis Truncated Hemoglobin N

by Ascenzi, Paolo, Coletta, Andrea, Cao, Yu, Trezza, Viviana, Leboffe, Loris, Fanali, Gabriella, Fasano, Mauro, Pesce, Alessandra, Ciaccio, Chiara, Marini, Stefano, Coletta, Massimo
Published 2013

Molecular mechanism of the camptothecin resistance of Glu710Gly topoisomerase IB mutant analyzed in vitro and in silico

by Tesauro, Cinzia, Morozzo della Rocca, Blasco, Ottaviani, Alessio, Coletta, Andrea, Zuccaro, Laura, Arnò, Barbara, D'Annessa, Ilda, Fiorani, Paola, Desideri, Alessandro
Published 2013