Design and analysis of clinical trials for predictive medicine

Bibliographic Details
Main Author: Matsui, Shigeyuki (Author)
Other Authors: Buyse, Marc E. (Editor), Simon, Richard M. , 1943 (Editor)
Format: Book
Language:English
Published: Boca Raton, Florida : CRC Press c2015
Series:Chapman & Hall/CRC biostatistics series
Subjects:
Table of Contents:
  • 1. Introductory overview
  • 2. Early clinical trials using biomarkers
  • 3. Phase III randomized clinical trials using biomarkers
  • 4. Analysis of high-dimensional data and genomic signature developments
  • 5. Randomized trials with biomarker development and validation
  • 6. Evaluation of surrogate biomarkers