Developing individualised therapy for colistin through application of pharmacokinetic model tailored for critically ill Malaysian patients utilizing the HPLC-FLD
Colistin is an antibiotic used as a last option to treat bacterial infections. Due to its toxicity, colistin is administered in the form of an inactive prodrug, colistin methanesulfonate sodium (CMS). The conversion of CMS to colistin in vivo varies greatly, leading to variations in plasma colistin...
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| Format: | Thesis |
| Language: | English |
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2025
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| Online Access: | http://eprints.usm.my/62793/ http://eprints.usm.my/62793/1/MOHD%20SHAFIE%20BIN%20ZABIDI-TESIS%20P-UD002019%28R%29-E.pdf |