Allele Frequencies ofF13AOI, FESFPS and vWA STRs in random Dusun population of Malaysia

Short Tandem Repeats (STRs) loci are characterized by high level of length polymorphism within and among populations. This polymorphism makes it becomes a blue print for forensic purposes. In this study, STR is applied for determining the allele's frequencies in Duson population in Sabah. Th...

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Main Author: Mohd Yusmaidie, Aziz
Format: Monograph
Language:English
Published: PPSP, Universiti Sains Malaysia 2007
Subjects:
Online Access:http://eprints.usm.my/50213/
http://eprints.usm.my/50213/1/MOHD%20YUSMAIDIE%20BIN%20AZIZ%20-%2024%20pages.pdf
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author Mohd Yusmaidie, Aziz
author_facet Mohd Yusmaidie, Aziz
author_sort Mohd Yusmaidie, Aziz
building USM Institutional Repository
collection Online Access
description Short Tandem Repeats (STRs) loci are characterized by high level of length polymorphism within and among populations. This polymorphism makes it becomes a blue print for forensic purposes. In this study, STR is applied for determining the allele's frequencies in Duson population in Sabah. This is done by using three different STR loci F13AOI, FESFPS and vWA. About 100 buccal swab samples from Dusun population were collected. Each sample was separated into different envelopes and sealed. Then DNA was extracted from the samples using simple procedure describe by Promega followed by STR typing on the three locus using multiplex kits. Allele frequencies were calculated and statistical analysis was then carried out. Comparative studies were carried out with referring to allele distribution from other populations. This study produces a database for random Duson population and hopefully will help in human identification in Malaysia. We also fid out that the genotype frequency distributions do not deviate from Hardy-Weinberg expectations.
first_indexed 2025-11-15T18:22:34Z
format Monograph
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institution Universiti Sains Malaysia
institution_category Local University
language English
last_indexed 2025-11-15T18:22:34Z
publishDate 2007
publisher PPSP, Universiti Sains Malaysia
recordtype eprints
repository_type Digital Repository
spelling usm-502132021-10-12T02:36:23Z http://eprints.usm.my/50213/ Allele Frequencies ofF13AOI, FESFPS and vWA STRs in random Dusun population of Malaysia Mohd Yusmaidie, Aziz R Medicine (General) Short Tandem Repeats (STRs) loci are characterized by high level of length polymorphism within and among populations. This polymorphism makes it becomes a blue print for forensic purposes. In this study, STR is applied for determining the allele's frequencies in Duson population in Sabah. This is done by using three different STR loci F13AOI, FESFPS and vWA. About 100 buccal swab samples from Dusun population were collected. Each sample was separated into different envelopes and sealed. Then DNA was extracted from the samples using simple procedure describe by Promega followed by STR typing on the three locus using multiplex kits. Allele frequencies were calculated and statistical analysis was then carried out. Comparative studies were carried out with referring to allele distribution from other populations. This study produces a database for random Duson population and hopefully will help in human identification in Malaysia. We also fid out that the genotype frequency distributions do not deviate from Hardy-Weinberg expectations. PPSP, Universiti Sains Malaysia 2007 Monograph NonPeerReviewed application/pdf en http://eprints.usm.my/50213/1/MOHD%20YUSMAIDIE%20BIN%20AZIZ%20-%2024%20pages.pdf Mohd Yusmaidie, Aziz (2007) Allele Frequencies ofF13AOI, FESFPS and vWA STRs in random Dusun population of Malaysia. Other. PPSP, Universiti Sains Malaysia. (Submitted)
spellingShingle R Medicine (General)
Mohd Yusmaidie, Aziz
Allele Frequencies ofF13AOI, FESFPS and vWA STRs in random Dusun population of Malaysia
title Allele Frequencies ofF13AOI, FESFPS and vWA STRs in random Dusun population of Malaysia
title_full Allele Frequencies ofF13AOI, FESFPS and vWA STRs in random Dusun population of Malaysia
title_fullStr Allele Frequencies ofF13AOI, FESFPS and vWA STRs in random Dusun population of Malaysia
title_full_unstemmed Allele Frequencies ofF13AOI, FESFPS and vWA STRs in random Dusun population of Malaysia
title_short Allele Frequencies ofF13AOI, FESFPS and vWA STRs in random Dusun population of Malaysia
title_sort allele frequencies off13aoi, fesfps and vwa strs in random dusun population of malaysia
topic R Medicine (General)
url http://eprints.usm.my/50213/
http://eprints.usm.my/50213/1/MOHD%20YUSMAIDIE%20BIN%20AZIZ%20-%2024%20pages.pdf