Antituberculosis: Synthesis and Antimycobacterial Activity of Novel Benzimidazole Derivatives

Antituberculosis: Synthesis and Antimycobacterial Activity of Novel Benzimidazole Derivatives

A total of seven novel benzimidazoles were synthesized by a 4-step reaction starting from 4-fluoro-3-nitrobenzoic acid under relatively mild reaction conditions.The synthesized compounds were screened for their antimycobacterial activity against M. tuberculosis H37Rv (MTB-H37Rv) and INH-resistant...

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Bibliographic Details
Main Authors: Yeong, Keng Yoon, Ali, Mohamed Ashraf, Tan, Soo Choon, Ismail, Rusli, Ang, Chee Wei, Kumar, Raju Suresh, Osman, Hasnah, Beevi, Farzana
Format: Article
Language:English
Published: Hindawi Publishing Corporation 2013
Subjects:
QD1-999 Chemistry
R735-854 Medical education. Medical schools. Research
Online Access:http://eprints.usm.my/38344/
http://eprints.usm.my/38344/1/Antituberculosis_Synthesis_and_Antimycobacterial_Activity_of_Novel_Benzimidazole_Derivatives.pdf

Internet

http://eprints.usm.my/38344/
http://eprints.usm.my/38344/1/Antituberculosis_Synthesis_and_Antimycobacterial_Activity_of_Novel_Benzimidazole_Derivatives.pdf

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