Post-partum streptococcal toxic shock syndrome associated with necrotizing fasciitis
We report a fatal case of post-partum streptococcal toxic shock syndrome in a patient who was previously healthy and had presented to the emergency department with an extensive blistering ecchymotic lesions over her right buttock and thigh associated with severe pain. The pregnancy had been uncomp...
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| Format: | Article |
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Elsevier
2017
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| Online Access: | http://eprints.usm.my/37160/ |
| _version_ | 1848878114013184000 |
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| author | Wei, Chuan Chua Mazlan, Mohd Zulfakar Ali, Saedah Che Omar, Sanihah Wan Hassan, Wan Mohd Nazaruddin Seevaunnantum, S. Praveena Mohd Zaini, Rhendra Hardy Hassan, Mohd Hasyizan Muhd Besari, Alwi Abd Rahman, Zaidah Ayub, Zeti Norfidiyati Salmuna Abd Ghani, Sabrina Yaacob, Normalinda Wan Rosli, Wan Rosilawati |
| author_facet | Wei, Chuan Chua Mazlan, Mohd Zulfakar Ali, Saedah Che Omar, Sanihah Wan Hassan, Wan Mohd Nazaruddin Seevaunnantum, S. Praveena Mohd Zaini, Rhendra Hardy Hassan, Mohd Hasyizan Muhd Besari, Alwi Abd Rahman, Zaidah Ayub, Zeti Norfidiyati Salmuna Abd Ghani, Sabrina Yaacob, Normalinda Wan Rosli, Wan Rosilawati |
| author_sort | Wei, Chuan Chua |
| building | USM Institutional Repository |
| collection | Online Access |
| description | We report a fatal case of post-partum streptococcal toxic shock syndrome in a patient who was previously
healthy and had presented to the emergency department with an extensive blistering ecchymotic lesions over her
right buttock and thigh associated with severe pain. The pregnancy had been uncomplicated, and the mode of
delivery had been spontaneous vaginal delivery with an episiotomy. She was found to have septicemic shock
requiring high inotropic support. Subsequently, she was treated for necrotizing fasciitis, complicated by septicemic
shock and multiple organ failures. A consensus was reached for extensive wound debridement to remove
the source of infection; however, this approach was abandoned due to the patient’s hemodynamic instability and
the extremely high risks of surgery. Both the high vaginal swab and blister fluid culture revealed Group A beta
hemolytic streptococcus infection. Intravenous carbapenem in combination with clindamycin was given. Other
strategies attempted for streptococcal toxic removal included continuous veno-venous hemofiltration and administration
of intravenous immunoglobulin. Unfortunately, the patient’s condition worsened, and she succumbed
to death on day 7 of hospitalization. |
| first_indexed | 2025-11-15T17:26:11Z |
| format | Article |
| id | usm-37160 |
| institution | Universiti Sains Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-15T17:26:11Z |
| publishDate | 2017 |
| publisher | Elsevier |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | usm-371602017-10-16T09:17:36Z http://eprints.usm.my/37160/ Post-partum streptococcal toxic shock syndrome associated with necrotizing fasciitis Wei, Chuan Chua Mazlan, Mohd Zulfakar Ali, Saedah Che Omar, Sanihah Wan Hassan, Wan Mohd Nazaruddin Seevaunnantum, S. Praveena Mohd Zaini, Rhendra Hardy Hassan, Mohd Hasyizan Muhd Besari, Alwi Abd Rahman, Zaidah Ayub, Zeti Norfidiyati Salmuna Abd Ghani, Sabrina Yaacob, Normalinda Wan Rosli, Wan Rosilawati RG Gynecology and obstetrics We report a fatal case of post-partum streptococcal toxic shock syndrome in a patient who was previously healthy and had presented to the emergency department with an extensive blistering ecchymotic lesions over her right buttock and thigh associated with severe pain. The pregnancy had been uncomplicated, and the mode of delivery had been spontaneous vaginal delivery with an episiotomy. She was found to have septicemic shock requiring high inotropic support. Subsequently, she was treated for necrotizing fasciitis, complicated by septicemic shock and multiple organ failures. A consensus was reached for extensive wound debridement to remove the source of infection; however, this approach was abandoned due to the patient’s hemodynamic instability and the extremely high risks of surgery. Both the high vaginal swab and blister fluid culture revealed Group A beta hemolytic streptococcus infection. Intravenous carbapenem in combination with clindamycin was given. Other strategies attempted for streptococcal toxic removal included continuous veno-venous hemofiltration and administration of intravenous immunoglobulin. Unfortunately, the patient’s condition worsened, and she succumbed to death on day 7 of hospitalization. Elsevier 2017 Article PeerReviewed Wei, Chuan Chua and Mazlan, Mohd Zulfakar and Ali, Saedah and Che Omar, Sanihah and Wan Hassan, Wan Mohd Nazaruddin and Seevaunnantum, S. Praveena and Mohd Zaini, Rhendra Hardy and Hassan, Mohd Hasyizan and Muhd Besari, Alwi and Abd Rahman, Zaidah and Ayub, Zeti Norfidiyati Salmuna and Abd Ghani, Sabrina and Yaacob, Normalinda and Wan Rosli, Wan Rosilawati (2017) Post-partum streptococcal toxic shock syndrome associated with necrotizing fasciitis. IDCases , 9. pp. 91-94. ISSN 2214-2509 https://doi.org/10.1016/j.idcr.2017.05.002 |
| spellingShingle | RG Gynecology and obstetrics Wei, Chuan Chua Mazlan, Mohd Zulfakar Ali, Saedah Che Omar, Sanihah Wan Hassan, Wan Mohd Nazaruddin Seevaunnantum, S. Praveena Mohd Zaini, Rhendra Hardy Hassan, Mohd Hasyizan Muhd Besari, Alwi Abd Rahman, Zaidah Ayub, Zeti Norfidiyati Salmuna Abd Ghani, Sabrina Yaacob, Normalinda Wan Rosli, Wan Rosilawati Post-partum streptococcal toxic shock syndrome associated with necrotizing fasciitis |
| title | Post-partum streptococcal toxic shock syndrome associated with necrotizing fasciitis |
| title_full | Post-partum streptococcal toxic shock syndrome associated with necrotizing fasciitis |
| title_fullStr | Post-partum streptococcal toxic shock syndrome associated with necrotizing fasciitis |
| title_full_unstemmed | Post-partum streptococcal toxic shock syndrome associated with necrotizing fasciitis |
| title_short | Post-partum streptococcal toxic shock syndrome associated with necrotizing fasciitis |
| title_sort | post-partum streptococcal toxic shock syndrome associated with necrotizing fasciitis |
| topic | RG Gynecology and obstetrics |
| url | http://eprints.usm.my/37160/ http://eprints.usm.my/37160/ |