Human iPS-derived pre-epicardial cells direct cardiomyocyte aggregation expansion and organization in vitro
Epicardial formation is necessary for normal myocardial morphogenesis. Here, we show that differentiating hiPSC-derived lateral plate mesoderm with BMP4, RA and VEGF (BVR) can generate a premature form of epicardial cells (termed pre-epicardial cells, PECs) expressing WT1, TBX18, SEMA3D, and SCX wit...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing
2021
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| Online Access: | http://psasir.upm.edu.my/id/eprint/97567/ http://psasir.upm.edu.my/id/eprint/97567/1/ABSTRACT.pdf |