Phytochemistry, pharmacological properties, and recent applications of Ficus benghalensis and Ficus religiosa

Ficus is one of the largest genera in the plant kingdom that belongs to the Moraceae family. This review aimed to summarize the medicinal uses, phytochemistry, and pharmacological actions of two major species from this genus, namely Ficus benghalensis and Ficus religiosa. These species can be found...

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Main Authors: Murugesu, Suganya, Selamat, Jinap, Perumal, Vikneswari
Format: Article
Published: Multidisciplinary Digital Publishing Institute 2021
Online Access:http://psasir.upm.edu.my/id/eprint/96260/
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author Murugesu, Suganya
Selamat, Jinap
Perumal, Vikneswari
author_facet Murugesu, Suganya
Selamat, Jinap
Perumal, Vikneswari
author_sort Murugesu, Suganya
building UPM Institutional Repository
collection Online Access
description Ficus is one of the largest genera in the plant kingdom that belongs to the Moraceae family. This review aimed to summarize the medicinal uses, phytochemistry, and pharmacological actions of two major species from this genus, namely Ficus benghalensis and Ficus religiosa. These species can be found abundantly in most Asian countries, including Malaysia. The chemical analysis report has shown that Ficus species contained a wide range of phytoconstituents, including phenols, flavonoids, alkaloids, tannins, saponins, terpenoids, glycosides, sugar, protein, essential and volatile oils, and steroids. Existing studies on the pharmacological functions have revealed that the observed Ficus species possessed a broad range of biological properties, including antioxidants, antidiabetic, anti-inflammatory, anticancer, antitumor and antiproliferative, antimutagenic, antimicrobial, anti-helminthic, hepatoprotective, wound healing, anticoagulant, immunomodulatory activities, antistress, toxicity studies, and mosquitocidal effects. Apart from the plant parts and their extracts, the endophytes residing in these host plants were discussed as well. This study also includes the recent applications of the Ficus species and their plant parts, mainly in the nanotechnology field. Various search engines and databases were used to obtain the scientific findings, including Google Scholar, ScienceDirect, PMC, Research Gate, and Scopus. Overall, the review discusses the therapeutic potentials discovered in recent times and highlights the research gaps for prospective research work.
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spelling upm-962602023-01-31T02:54:16Z http://psasir.upm.edu.my/id/eprint/96260/ Phytochemistry, pharmacological properties, and recent applications of Ficus benghalensis and Ficus religiosa Murugesu, Suganya Selamat, Jinap Perumal, Vikneswari Ficus is one of the largest genera in the plant kingdom that belongs to the Moraceae family. This review aimed to summarize the medicinal uses, phytochemistry, and pharmacological actions of two major species from this genus, namely Ficus benghalensis and Ficus religiosa. These species can be found abundantly in most Asian countries, including Malaysia. The chemical analysis report has shown that Ficus species contained a wide range of phytoconstituents, including phenols, flavonoids, alkaloids, tannins, saponins, terpenoids, glycosides, sugar, protein, essential and volatile oils, and steroids. Existing studies on the pharmacological functions have revealed that the observed Ficus species possessed a broad range of biological properties, including antioxidants, antidiabetic, anti-inflammatory, anticancer, antitumor and antiproliferative, antimutagenic, antimicrobial, anti-helminthic, hepatoprotective, wound healing, anticoagulant, immunomodulatory activities, antistress, toxicity studies, and mosquitocidal effects. Apart from the plant parts and their extracts, the endophytes residing in these host plants were discussed as well. This study also includes the recent applications of the Ficus species and their plant parts, mainly in the nanotechnology field. Various search engines and databases were used to obtain the scientific findings, including Google Scholar, ScienceDirect, PMC, Research Gate, and Scopus. Overall, the review discusses the therapeutic potentials discovered in recent times and highlights the research gaps for prospective research work. Multidisciplinary Digital Publishing Institute 2021 Article PeerReviewed Murugesu, Suganya and Selamat, Jinap and Perumal, Vikneswari (2021) Phytochemistry, pharmacological properties, and recent applications of Ficus benghalensis and Ficus religiosa. Plants-Basel, 10 (12). art. no. 2749. pp. 1-29. ISSN 2223-7747 https://www.mdpi.com/2223-7747/10/12/2749 10.3390/plants10122749
spellingShingle Murugesu, Suganya
Selamat, Jinap
Perumal, Vikneswari
Phytochemistry, pharmacological properties, and recent applications of Ficus benghalensis and Ficus religiosa
title Phytochemistry, pharmacological properties, and recent applications of Ficus benghalensis and Ficus religiosa
title_full Phytochemistry, pharmacological properties, and recent applications of Ficus benghalensis and Ficus religiosa
title_fullStr Phytochemistry, pharmacological properties, and recent applications of Ficus benghalensis and Ficus religiosa
title_full_unstemmed Phytochemistry, pharmacological properties, and recent applications of Ficus benghalensis and Ficus religiosa
title_short Phytochemistry, pharmacological properties, and recent applications of Ficus benghalensis and Ficus religiosa
title_sort phytochemistry, pharmacological properties, and recent applications of ficus benghalensis and ficus religiosa
url http://psasir.upm.edu.my/id/eprint/96260/
http://psasir.upm.edu.my/id/eprint/96260/
http://psasir.upm.edu.my/id/eprint/96260/