A review on Haematococcus pluvialis bioprocess optimization of green and red Stage culture conditions for the production of natural astaxanthin
As the most recognizable natural secondary carotenoid astaxanthin producer, the green microalga Haematococcus pluvialis cultivation is performed via a two-stage process. The first is dedicated to biomass accumulation under growth-favoring conditions (green stage), and the second stage is for astaxan...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
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Multidisciplinary Digital Publishing Institute
2021
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| Online Access: | http://psasir.upm.edu.my/id/eprint/96026/ |
| _version_ | 1848862281717252096 |
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| author | Oslan, Siti Nur Hazwani Shoparwe, Noor Fazliani Yusoff, Abdul Hafidz Abdul Rahim, Ainihayati Chang, Shen Chang Tan, Joo Shun Oslan, Siti Nurbaya Arumugam, Kavithraashree Ariff, Arbakariya Sulaiman, Ahmad Ziad Mohamed, Mohd Shamzi |
| author_facet | Oslan, Siti Nur Hazwani Shoparwe, Noor Fazliani Yusoff, Abdul Hafidz Abdul Rahim, Ainihayati Chang, Shen Chang Tan, Joo Shun Oslan, Siti Nurbaya Arumugam, Kavithraashree Ariff, Arbakariya Sulaiman, Ahmad Ziad Mohamed, Mohd Shamzi |
| author_sort | Oslan, Siti Nur Hazwani |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | As the most recognizable natural secondary carotenoid astaxanthin producer, the green microalga Haematococcus pluvialis cultivation is performed via a two-stage process. The first is dedicated to biomass accumulation under growth-favoring conditions (green stage), and the second stage is for astaxanthin evolution under various stress conditions (red stage). This mini-review discusses the further improvement made on astaxanthin production by providing an overview of recent works on H. pluvialis, including the valuable ideas for bioprocess optimization on cell growth, and the current stress-exerting strategies for astaxanthin pigment production. The effects of nutrient constituents, especially nitrogen and carbon sources, and illumination intensity are emphasized during the green stage. On the other hand, the significance of the nitrogen depletion strategy and other exogenous factors comprising salinity, illumination, and temperature are considered for the astaxanthin inducement during the red stage. In short, any factor that interferes with the cellular processes that limit the growth or photosynthesis in the green stage could trigger the encystment process and astaxanthin formation during the red stage. This review provides an insight regarding the parameters involved in bioprocess optimization for high-value astaxanthin biosynthesis from H. pluvialis. |
| first_indexed | 2025-11-15T13:14:32Z |
| format | Article |
| id | upm-96026 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-15T13:14:32Z |
| publishDate | 2021 |
| publisher | Multidisciplinary Digital Publishing Institute |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-960262023-02-24T08:28:23Z http://psasir.upm.edu.my/id/eprint/96026/ A review on Haematococcus pluvialis bioprocess optimization of green and red Stage culture conditions for the production of natural astaxanthin Oslan, Siti Nur Hazwani Shoparwe, Noor Fazliani Yusoff, Abdul Hafidz Abdul Rahim, Ainihayati Chang, Shen Chang Tan, Joo Shun Oslan, Siti Nurbaya Arumugam, Kavithraashree Ariff, Arbakariya Sulaiman, Ahmad Ziad Mohamed, Mohd Shamzi As the most recognizable natural secondary carotenoid astaxanthin producer, the green microalga Haematococcus pluvialis cultivation is performed via a two-stage process. The first is dedicated to biomass accumulation under growth-favoring conditions (green stage), and the second stage is for astaxanthin evolution under various stress conditions (red stage). This mini-review discusses the further improvement made on astaxanthin production by providing an overview of recent works on H. pluvialis, including the valuable ideas for bioprocess optimization on cell growth, and the current stress-exerting strategies for astaxanthin pigment production. The effects of nutrient constituents, especially nitrogen and carbon sources, and illumination intensity are emphasized during the green stage. On the other hand, the significance of the nitrogen depletion strategy and other exogenous factors comprising salinity, illumination, and temperature are considered for the astaxanthin inducement during the red stage. In short, any factor that interferes with the cellular processes that limit the growth or photosynthesis in the green stage could trigger the encystment process and astaxanthin formation during the red stage. This review provides an insight regarding the parameters involved in bioprocess optimization for high-value astaxanthin biosynthesis from H. pluvialis. Multidisciplinary Digital Publishing Institute 2021 Article PeerReviewed Oslan, Siti Nur Hazwani and Shoparwe, Noor Fazliani and Yusoff, Abdul Hafidz and Abdul Rahim, Ainihayati and Chang, Shen Chang and Tan, Joo Shun and Oslan, Siti Nurbaya and Arumugam, Kavithraashree and Ariff, Arbakariya and Sulaiman, Ahmad Ziad and Mohamed, Mohd Shamzi (2021) A review on Haematococcus pluvialis bioprocess optimization of green and red Stage culture conditions for the production of natural astaxanthin. Biomolecules, 11 (2). art. no. 256. pp. 1-15. ISSN 2218-273X https://www.mdpi.com/2218-273X/11/2/256 10.3390/biom11020256 |
| spellingShingle | Oslan, Siti Nur Hazwani Shoparwe, Noor Fazliani Yusoff, Abdul Hafidz Abdul Rahim, Ainihayati Chang, Shen Chang Tan, Joo Shun Oslan, Siti Nurbaya Arumugam, Kavithraashree Ariff, Arbakariya Sulaiman, Ahmad Ziad Mohamed, Mohd Shamzi A review on Haematococcus pluvialis bioprocess optimization of green and red Stage culture conditions for the production of natural astaxanthin |
| title | A review on Haematococcus pluvialis bioprocess optimization of green and red Stage culture conditions for the production of natural astaxanthin |
| title_full | A review on Haematococcus pluvialis bioprocess optimization of green and red Stage culture conditions for the production of natural astaxanthin |
| title_fullStr | A review on Haematococcus pluvialis bioprocess optimization of green and red Stage culture conditions for the production of natural astaxanthin |
| title_full_unstemmed | A review on Haematococcus pluvialis bioprocess optimization of green and red Stage culture conditions for the production of natural astaxanthin |
| title_short | A review on Haematococcus pluvialis bioprocess optimization of green and red Stage culture conditions for the production of natural astaxanthin |
| title_sort | review on haematococcus pluvialis bioprocess optimization of green and red stage culture conditions for the production of natural astaxanthin |
| url | http://psasir.upm.edu.my/id/eprint/96026/ http://psasir.upm.edu.my/id/eprint/96026/ http://psasir.upm.edu.my/id/eprint/96026/ |