Inconsistency of lesion quantitative assessment in 2D SUV and 3D SUV quantification techniques for [18F]-FDG PET/CT: a phantom study

This study was performed to assess the inconsistency of lesion quantification in standardised uptake value (SUV) [ 18F]-FDG between Ellipse (2-Dimensional) and Ellipsoid (3-Dimensional) quantification techniques by using PET/ CT image quality phantom. Reconstructed images of PET/CT ACR phantom was u...

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Main Authors: Hanafi, Muhammad Hafiz, Mohd Noor, Noramaliza, Hassan, Muhammad Hishar
Format: Article
Language:English
Published: Faculty of Medicine and Health Sciences, Universiti Putra Malaysia 2021
Online Access:http://psasir.upm.edu.my/id/eprint/90358/
http://psasir.upm.edu.my/id/eprint/90358/1/2021040613542341_MJMHS_0665.pdf
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author Hanafi, Muhammad Hafiz
Mohd Noor, Noramaliza
Hassan, Muhammad Hishar
author_facet Hanafi, Muhammad Hafiz
Mohd Noor, Noramaliza
Hassan, Muhammad Hishar
author_sort Hanafi, Muhammad Hafiz
building UPM Institutional Repository
collection Online Access
description This study was performed to assess the inconsistency of lesion quantification in standardised uptake value (SUV) [ 18F]-FDG between Ellipse (2-Dimensional) and Ellipsoid (3-Dimensional) quantification techniques by using PET/ CT image quality phantom. Reconstructed images of PET/CT ACR phantom was used to assess the quantification of SUV (SUVmax, SUVavg and SUVmin) on selected regions of interest. Statistical analysis of paired t-test was performed to compare the lesion quantification in SUV [18F]-FDG between 2D and 3D techniques. The quantification techniques were consistently similar of assessment between 2D SUVmax and 3D SUVmax at 12mm of ROI lesion with [(0.00 ± 0.02), t(29)=-0.48, p>0.05]. However, the rest of quantification techniques of 2D SUVmax, 3D SUVmax, 2D SUVavg, 3D SUVavg, 2D SUVmin and 3D SUVmin, results shown significant inconsistency since the p >0.05]. However, the rest of quantification techniques of 2D SUVmax, 3D SUVmax, 2D SUVavg, 3D SUVavg, 2D SUVmin and 3D SUVmin, results shown significant inconsistency since the p<0.05. This phantom study has proven that there were inconsistency of lesion quantitative assessment in 2D SUV and 3D SUV quantification techniques for [18F]-FDG PET/CT.
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spelling upm-903582021-09-10T01:01:18Z http://psasir.upm.edu.my/id/eprint/90358/ Inconsistency of lesion quantitative assessment in 2D SUV and 3D SUV quantification techniques for [18F]-FDG PET/CT: a phantom study Hanafi, Muhammad Hafiz Mohd Noor, Noramaliza Hassan, Muhammad Hishar This study was performed to assess the inconsistency of lesion quantification in standardised uptake value (SUV) [ 18F]-FDG between Ellipse (2-Dimensional) and Ellipsoid (3-Dimensional) quantification techniques by using PET/ CT image quality phantom. Reconstructed images of PET/CT ACR phantom was used to assess the quantification of SUV (SUVmax, SUVavg and SUVmin) on selected regions of interest. Statistical analysis of paired t-test was performed to compare the lesion quantification in SUV [18F]-FDG between 2D and 3D techniques. The quantification techniques were consistently similar of assessment between 2D SUVmax and 3D SUVmax at 12mm of ROI lesion with [(0.00 ± 0.02), t(29)=-0.48, p>0.05]. However, the rest of quantification techniques of 2D SUVmax, 3D SUVmax, 2D SUVavg, 3D SUVavg, 2D SUVmin and 3D SUVmin, results shown significant inconsistency since the p >0.05]. However, the rest of quantification techniques of 2D SUVmax, 3D SUVmax, 2D SUVavg, 3D SUVavg, 2D SUVmin and 3D SUVmin, results shown significant inconsistency since the p<0.05. This phantom study has proven that there were inconsistency of lesion quantitative assessment in 2D SUV and 3D SUV quantification techniques for [18F]-FDG PET/CT. Faculty of Medicine and Health Sciences, Universiti Putra Malaysia 2021-04 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/90358/1/2021040613542341_MJMHS_0665.pdf Hanafi, Muhammad Hafiz and Mohd Noor, Noramaliza and Hassan, Muhammad Hishar (2021) Inconsistency of lesion quantitative assessment in 2D SUV and 3D SUV quantification techniques for [18F]-FDG PET/CT: a phantom study. Malaysian Journal of Medicine and Health Sciences, 17 (2). pp. 289-293. ISSN 1675-8544; ESSN: 2636-9346 https://medic.upm.edu.my/upload/dokumen/2021040613542341_MJMHS_0665.pdf
spellingShingle Hanafi, Muhammad Hafiz
Mohd Noor, Noramaliza
Hassan, Muhammad Hishar
Inconsistency of lesion quantitative assessment in 2D SUV and 3D SUV quantification techniques for [18F]-FDG PET/CT: a phantom study
title Inconsistency of lesion quantitative assessment in 2D SUV and 3D SUV quantification techniques for [18F]-FDG PET/CT: a phantom study
title_full Inconsistency of lesion quantitative assessment in 2D SUV and 3D SUV quantification techniques for [18F]-FDG PET/CT: a phantom study
title_fullStr Inconsistency of lesion quantitative assessment in 2D SUV and 3D SUV quantification techniques for [18F]-FDG PET/CT: a phantom study
title_full_unstemmed Inconsistency of lesion quantitative assessment in 2D SUV and 3D SUV quantification techniques for [18F]-FDG PET/CT: a phantom study
title_short Inconsistency of lesion quantitative assessment in 2D SUV and 3D SUV quantification techniques for [18F]-FDG PET/CT: a phantom study
title_sort inconsistency of lesion quantitative assessment in 2d suv and 3d suv quantification techniques for [18f]-fdg pet/ct: a phantom study
url http://psasir.upm.edu.my/id/eprint/90358/
http://psasir.upm.edu.my/id/eprint/90358/
http://psasir.upm.edu.my/id/eprint/90358/1/2021040613542341_MJMHS_0665.pdf