Interactions between food hazards and intestinal barrier: impact on foodborne diseases
The intestine is an important digestive organ of the human body, and its barrier is the guardian of the body from the external environment. The impairment of the intestinal barrier is believed to be an important determinant in various foodborne diseases. Food hazards can lead to the occurrence of ma...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
American Chemical Society
2020
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| Online Access: | http://psasir.upm.edu.my/id/eprint/89425/ http://psasir.upm.edu.my/id/eprint/89425/1/FOOD.pdf |
| _version_ | 1848860851305447424 |
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| author | Li, Xue Tan, Chin Ping Liu, Yuan Fa Xu, Yong Jiang |
| author_facet | Li, Xue Tan, Chin Ping Liu, Yuan Fa Xu, Yong Jiang |
| author_sort | Li, Xue |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | The intestine is an important digestive organ of the human body, and its barrier is the guardian of the body from the external environment. The impairment of the intestinal barrier is believed to be an important determinant in various foodborne diseases. Food hazards can lead to the occurrence of many foodborne diseases represented by inflammation. Therefore, understanding the mechanisms of the impact of the food hazards on intestinal barriers is essential for promoting human health. This review examined the relationship between food hazards and the intestinal barrier in three aspects: apoptosis, imbalance of gut microbiota, and pro-inflammatory cytokines. The mechanism of dysfunctional gut microbiota caused by food hazards was also discussed. This review discusses the interaction among food hazards, intestinal barrier, and foodborne diseases and, thus, offers a new thought to deal with foodborne disease. |
| first_indexed | 2025-11-15T12:51:48Z |
| format | Article |
| id | upm-89425 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T12:51:48Z |
| publishDate | 2020 |
| publisher | American Chemical Society |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-894252021-08-18T10:01:37Z http://psasir.upm.edu.my/id/eprint/89425/ Interactions between food hazards and intestinal barrier: impact on foodborne diseases Li, Xue Tan, Chin Ping Liu, Yuan Fa Xu, Yong Jiang The intestine is an important digestive organ of the human body, and its barrier is the guardian of the body from the external environment. The impairment of the intestinal barrier is believed to be an important determinant in various foodborne diseases. Food hazards can lead to the occurrence of many foodborne diseases represented by inflammation. Therefore, understanding the mechanisms of the impact of the food hazards on intestinal barriers is essential for promoting human health. This review examined the relationship between food hazards and the intestinal barrier in three aspects: apoptosis, imbalance of gut microbiota, and pro-inflammatory cytokines. The mechanism of dysfunctional gut microbiota caused by food hazards was also discussed. This review discusses the interaction among food hazards, intestinal barrier, and foodborne diseases and, thus, offers a new thought to deal with foodborne disease. American Chemical Society 2020 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/89425/1/FOOD.pdf Li, Xue and Tan, Chin Ping and Liu, Yuan Fa and Xu, Yong Jiang (2020) Interactions between food hazards and intestinal barrier: impact on foodborne diseases. Journal of Agricultural and Food Chemistry, 68 (50). 14728 - 14738. ISSN 0021-8561; ESSN: 1520-5118 https://pubs.acs.org/doi/10.1021/acs.jafc.0c07378 10.1021/acs.jafc.0c07378 |
| spellingShingle | Li, Xue Tan, Chin Ping Liu, Yuan Fa Xu, Yong Jiang Interactions between food hazards and intestinal barrier: impact on foodborne diseases |
| title | Interactions between food hazards and intestinal barrier: impact on foodborne diseases |
| title_full | Interactions between food hazards and intestinal barrier: impact on foodborne diseases |
| title_fullStr | Interactions between food hazards and intestinal barrier: impact on foodborne diseases |
| title_full_unstemmed | Interactions between food hazards and intestinal barrier: impact on foodborne diseases |
| title_short | Interactions between food hazards and intestinal barrier: impact on foodborne diseases |
| title_sort | interactions between food hazards and intestinal barrier: impact on foodborne diseases |
| url | http://psasir.upm.edu.my/id/eprint/89425/ http://psasir.upm.edu.my/id/eprint/89425/ http://psasir.upm.edu.my/id/eprint/89425/ http://psasir.upm.edu.my/id/eprint/89425/1/FOOD.pdf |