Analytical method development and validation of anticancer agent, 5-fluorouracil, and its metabolites in biological matrices: an updated review

QR Code

Analytical method development and validation of anticancer agent, 5-fluorouracil, and its metabolites in biological matrices: an updated review

5-fluorouracil (5-FU) refers to a fluorinated pyrimidine analogue that has been widely used as an anticancer agent for colon, head, and neck cancers. Detection of 5-FU and its metabolites; 5-fluorouridine and 5-fluoro-2-deoxyuridine in biological samples allows optimization of pharmacotherapy and en...

Full description

Bibliographic Details
Main Authors:	Semail, Nadhiratul farihin, Abdul Keyon, Aemi Syazwani, Saad, Bahruddin, Noordin, Siti Salmah, Nik Mohamed Kamal, Nik Nur Syazni, Mohamad Zain, Nur Nadhirah, Azizi, Juzaili, Kamaruzaman, Sazlinda, Yahaya, Noorfatimah
Format:	Article
Language:	English
Published:	Taylor and Francis 2020
Online Access:	http://psasir.upm.edu.my/id/eprint/87877/ http://psasir.upm.edu.my/id/eprint/87877/1/ABSTRACT.pdf

Similar Items

A simple and efficient sequential electrokinetic and hydrodynamic injections in micellar electrokinetic chromatography method for quantification of anticancer drug 5-fluorouracil and its metabolite in human plasma
by: Semail, Nadhiratul farihin, et al.
Published: (2021)

Development And Validation Of Online Preconcentration Capillary Electrophoresis Methods For The Determination Of Selected Pharmaceutical Compounds In Aqueous Matrices
by: Semail, Nadhiratul-Farihin
Published: (2022)

Induced sample via transient isotachophoresis mediated with sweeping in micellar electrokinetic chromatography for the dual-stacking strategy of non-steroidal anti-inflammatory drugs in environmental water samples
by: Semail, Nadhiratul Farihin, et al.
Published: (2022)

Simple and sensitive electrokinetic supercharging in capillary electrophoresis for online preconcentration and separation of secbumeton in water samples
by: Soeung, Rasmey, et al.
Published: (2020)

Recent advances in solid phase extraction methods for the determination of bisphenol A and its analogues in environmental matrices: an updated review
by: Mohd Ali, Nur Farahin, et al.
Published: (2023)

Rapid ultrasound assisted emulsification micro-solid phase extraction based on molecularly imprinted polymer for HPLC-DAD determination of bisphenol A in aqueous matrices
by: Rozaini, Muhammad Nur’ Hafiz, et al.
Published: (2017)

Molecularly imprinted silica gel incorporated with agarose polymer matrix as mixed matrix membrane for separation and preconcentration of sulfonamide antibiotics in water samples
by: Rozaini, Muhammad Nur’ Hafiz, et al.
Published: (2019)

Advances in dispersive solid-phase extraction techniques for analytical quantification of fluoroquinolone antibiotics
by: Syaleyana Md Shukri, Dyia, et al.
Published: (2023)

The potential anticancer activity of 5-fluorouracil loaded in cellulose fibers isolated from rice straw
by: Yusefi, Mostafa, et al.
Published: (2020)

Endophytic fungi and bioactive metabolites production: an update
by: Sinniah, Uma Rani, et al.
Published: (2018)

Di-Block PLCL and Tri-Block PLCLG matrix polymeric nanoparticles enhanced the anticancer activity of loaded 5-fluorouracil
by: Ashour, Abdelkader Elbadawy Abbas, et al.
Published: (2016)

Recent developments in synthesis and characterisation of graphene oxide modified with deep eutectic solvents for dispersive and magnetic solid-phase extractions
by: Emmanuel Ibukun, Aduloju, et al.
Published: (2024)

Micro-extraction of xenobiotics and biomolecules from different matrices on nanostructures
by: Sanagi, Mohd Marsin, et al.
Published: (2016)

Microextraction of Xenobiotics and Biomolecules from Different Matrices on Nano Structures
by: Sanagi, Mohd Marsin, et al.
Published: (2014)

Doxorubicin: an update on anticancer molecular action, toxicity and novel drug delivery systems
by: Tacar, O., et al.
Published: (2013)

Parikh Matrices
by: Ng , Yin Yin
Published: (2008)

Chitosan-Nanoparticles As A Drug Delivery System For 5-Fluorouracil
by: Suardi, Muslim
Published: (2003)

An in vitro anticancer activity evaluation of Neolamarckia cadamba (Roxb.) bosser leaves extract and its metabolite profile
by: Razali, Shakirah, et al.
Published: (2021)

Spectral operators of matrices
by: Ding, C., et al.
Published: (2017)

Biodegradable Matrices and Composites
Published: (2020)

On G-Decomposition of matrices
by: Mukhamedov, Farrukh
Published: (2011)

Dispersive liquid–liquid microextraction combined with dispersive solid-phase extraction for gas chromatography with mass spectrometry determination of polycyclic aromatic hydrocarbons in aqueous matrices
by: Mohd Hassan, Farah Wahidah, et al.
Published: (2018)

Metabolomics and pharmacogenetics based 5-fluorouracil monitoring in colorectal cancer patients
by: Zakaria, Bannur, et al.
Published: (2014)

Metabolomics and pharmacogenetics based 5-fluorouracil monitoring in colorectal cancer patients
by: Bannur, Zakaria, et al.
Published: (2014)

Predicting group of metabolites available in partially purified tomato leaves extract showing anticancer activity by HPLC and FTIR
by: Wan Chik, Wan Dalila, et al.
Published: (2011)

Characterisation of cucumber mosaic virus (CMV) in Catharanthus roseus (L.)G. don and its effects on anticancer metabolite production
by: Mat, Mazidah
Published: (2012)

Editorial: Biodegradable Matrices and Composites
by: Pegoretti, Alessandro, et al.
Published: (2020)

Physical pegylation enhances the cytotoxicity of 5-fluorouracil-loaded PLGA And PCL nanoparticles.
by: Ashour, Abdelkader Elbadawy Abbas, et al.
Published: (2019)

5-fluorouracil loaded magnetic cellulose bionanocomposites for potential colorectal cancer treatment
by: Yusefi, Mostafa, et al.
Published: (2021)

Selection of culture conditions through manipulation of physical and chemical parameters for production of high-value metabolites in marine microalga Tetraselmis tetrathele (West) butcher 1959 biomass
by: Abd Wahab, Nurul Farihin
Published: (2021)

Mitochondrial DNA quantity changes in leucocytes of cancer patients on cisplatin and 5-fluorouracil regimen
by: Khaing, Ei Phyo, et al.
Published: (2016)

The Thermal Stability of Lattice-Energy Minima of 5-Fluorouracil: Metadynamics as an Aid to Polymorph Prediction
by: Karamertzanis, P., et al.
Published: (2008)

Microencapsulation of gentamicin into PLGA-chitosan matrices
by: Abdullah Hazim, Anas, et al.
Published: (2011)

On the conjugate product of complex polynomial matrices
by: Wu, A., et al.
Published: (2011)

Truncated Boolean Matrices For Dna Computation
by: Nordiana, Rajaee, et al.
Published: (2014)

Application of a new choline-imidazole based deep eutectic solvents in hybrid magnetic molecularly imprinted polymer for efficient and selective removal of naproxen from aqueous samples
by: Husin, Nor Aniisah, et al.
Published: (2021)

Potential of dihydropyrimidine dehydrogenase genotypes in personalising 5-fluorouracil therapy among colorectal cancer patients
by: Ngow, Harris Abdullah, et al.
Published: (2011)

Notch-induced transcription factors are predictive of survival and 5-fluorouracil response in colorectal cancer patients
by: Candy, P., et al.
Published: (2013)

Potential of dihydropyrimidine dehydrogenase genotypes in personalizing 5-fluorouracil therapy among colorectal cancer patients
by: Teh, Lay Kek, et al.
Published: (2013)

Inclusion of curcumin in β-cyclodextrins as potential drug delivery system: preparation, characterization and its preliminary cytotoxicity approaches
by: Muhammad Hasnor Ja'far,, et al.
Published: (2018)