Analytical method development and validation of anticancer agent, 5-fluorouracil, and its metabolites in biological matrices: an updated review
5-fluorouracil (5-FU) refers to a fluorinated pyrimidine analogue that has been widely used as an anticancer agent for colon, head, and neck cancers. Detection of 5-FU and its metabolites; 5-fluorouridine and 5-fluoro-2-deoxyuridine in biological samples allows optimization of pharmacotherapy and en...
| Main Authors: | , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Taylor and Francis
2020
|
| Online Access: | http://psasir.upm.edu.my/id/eprint/87877/ http://psasir.upm.edu.my/id/eprint/87877/1/ABSTRACT.pdf |