Mycobiome in the gut: a multi-perspective review
Human gut is home to a diverse and complex microbial ecosystem encompassing bacteria, viruses, parasites, fungi, and other microorganisms that have an undisputable role in maintaining good health for the host. Studies on the interplay between microbiota in the gut and various human diseases remain t...
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| Format: | Article |
| Language: | English |
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Hindawi
2020
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| Online Access: | http://psasir.upm.edu.my/id/eprint/86870/ http://psasir.upm.edu.my/id/eprint/86870/1/Mycobiome.pdf |
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| author | Chin, Voon Kin Yong, Voon Chen Chong, Pei Pei Amin Nordin, Syafinaz Basir, Rusliza Abdullah, Maha |
| author_facet | Chin, Voon Kin Yong, Voon Chen Chong, Pei Pei Amin Nordin, Syafinaz Basir, Rusliza Abdullah, Maha |
| author_sort | Chin, Voon Kin |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Human gut is home to a diverse and complex microbial ecosystem encompassing bacteria, viruses, parasites, fungi, and other microorganisms that have an undisputable role in maintaining good health for the host. Studies on the interplay between microbiota in the gut and various human diseases remain the key focus among many researchers. Nevertheless, advances in sequencing technologies and computational biology have helped us to identify a diversity of fungal community that reside in the gut known as the mycobiome. Although studies on gut mycobiome are still in its infancy, numerous sources have reported its potential role in host homeostasis and disease development. Nonetheless, the actual mechanism of its involvement remains largely unknown and underexplored. Thus, in this review, we attempt to discuss the recent advances in gut mycobiome research from multiple perspectives. This includes understanding the composition of fungal communities in the gut and the involvement of gut mycobiome in host immunity and gut-brain axis. Further, we also discuss on multibiome interactions in the gut with emphasis on fungi-bacteria interaction and the influence of diet in shaping gut mycobiome composition. This review also highlights the relation between fungal metabolites and gut mycobiota in human homeostasis and the role of gut mycobiome in various human diseases. This multiperspective review on gut mycobiome could perhaps shed new light for future studies in the mycobiome research area. |
| first_indexed | 2025-11-15T12:43:11Z |
| format | Article |
| id | upm-86870 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T12:43:11Z |
| publishDate | 2020 |
| publisher | Hindawi |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-868702021-12-29T04:18:54Z http://psasir.upm.edu.my/id/eprint/86870/ Mycobiome in the gut: a multi-perspective review Chin, Voon Kin Yong, Voon Chen Chong, Pei Pei Amin Nordin, Syafinaz Basir, Rusliza Abdullah, Maha Human gut is home to a diverse and complex microbial ecosystem encompassing bacteria, viruses, parasites, fungi, and other microorganisms that have an undisputable role in maintaining good health for the host. Studies on the interplay between microbiota in the gut and various human diseases remain the key focus among many researchers. Nevertheless, advances in sequencing technologies and computational biology have helped us to identify a diversity of fungal community that reside in the gut known as the mycobiome. Although studies on gut mycobiome are still in its infancy, numerous sources have reported its potential role in host homeostasis and disease development. Nonetheless, the actual mechanism of its involvement remains largely unknown and underexplored. Thus, in this review, we attempt to discuss the recent advances in gut mycobiome research from multiple perspectives. This includes understanding the composition of fungal communities in the gut and the involvement of gut mycobiome in host immunity and gut-brain axis. Further, we also discuss on multibiome interactions in the gut with emphasis on fungi-bacteria interaction and the influence of diet in shaping gut mycobiome composition. This review also highlights the relation between fungal metabolites and gut mycobiota in human homeostasis and the role of gut mycobiome in various human diseases. This multiperspective review on gut mycobiome could perhaps shed new light for future studies in the mycobiome research area. Hindawi 2020-04-04 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/86870/1/Mycobiome.pdf Chin, Voon Kin and Yong, Voon Chen and Chong, Pei Pei and Amin Nordin, Syafinaz and Basir, Rusliza and Abdullah, Maha (2020) Mycobiome in the gut: a multi-perspective review. Mediators of Inflammation, 2020. art. no. 9560684. pp. 1-16. ISSN 0962-9351; ESSN: 1466-1861 https://www.hindawi.com/journals/mi/2020/9560684/ 10.1155/2020/9560684 |
| spellingShingle | Chin, Voon Kin Yong, Voon Chen Chong, Pei Pei Amin Nordin, Syafinaz Basir, Rusliza Abdullah, Maha Mycobiome in the gut: a multi-perspective review |
| title | Mycobiome in the gut: a multi-perspective review |
| title_full | Mycobiome in the gut: a multi-perspective review |
| title_fullStr | Mycobiome in the gut: a multi-perspective review |
| title_full_unstemmed | Mycobiome in the gut: a multi-perspective review |
| title_short | Mycobiome in the gut: a multi-perspective review |
| title_sort | mycobiome in the gut: a multi-perspective review |
| url | http://psasir.upm.edu.my/id/eprint/86870/ http://psasir.upm.edu.my/id/eprint/86870/ http://psasir.upm.edu.my/id/eprint/86870/ http://psasir.upm.edu.my/id/eprint/86870/1/Mycobiome.pdf |