Effects of postbiotic supplementation on growth performance, ruminal fermentation and microbial profile, blood metabolite and GHR, IGF-1 and MCT-1 gene expression in post-weaning lambs
Background: Postbiotics have been established as potential feed additive to be used in monogastric such as poultry and swine to enhance health and growth performance. However, information on the postbiotics as feed additive in ruminants is very limited. The aim of this study was to elucidate the eff...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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BioMed Central
2019
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| Online Access: | http://psasir.upm.edu.my/id/eprint/79614/ http://psasir.upm.edu.my/id/eprint/79614/1/Effects%20of%20postbiotic%20supplementation%20on%20growth%20performance.pdf |
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| author | Wan Ibrahim, Izuddin Loh, Teck Chwen Samsudin, Anjas Asmara @ Ab Hadi Foo, Hooi Ling Merzza, Humam Ali Shazali, Nurhazirah |
| author_facet | Wan Ibrahim, Izuddin Loh, Teck Chwen Samsudin, Anjas Asmara @ Ab Hadi Foo, Hooi Ling Merzza, Humam Ali Shazali, Nurhazirah |
| author_sort | Wan Ibrahim, Izuddin |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Background: Postbiotics have been established as potential feed additive to be used in monogastric such as poultry and swine to enhance health and growth performance. However, information on the postbiotics as feed additive in ruminants is very limited. The aim of this study was to elucidate the effects of supplementation of postbiotics in newly-weaned lambs on growth performance, digestibility, rumen fermentation characteristics and microbial population, blood metabolite and expression of genes related to growth and volatile fatty acid transport across the rumen epithelium. Results: Postbiotic supplementation increased weight gain, feed intake, nutrient intake and nutrient digestibility of the lambs. No effect on ruminal pH and total VFA, whereas butyrate and ruminal ammonia-N concentration were improved. The lambs fed with postbiotics had higher blood total protein, urea nitrogen and glucose. However, no difference was observed in blood triglycerides and cholesterol levels. Postbiotics increased the population of fibre degrading bacteria but decreased total protozoa and methanogens in rumen. Postbiotics increased the mRNA expression of hepatic IGF-1 and ruminal MCT-1. Conclusions: The inclusion of postbiotics from L. plantarum RG14 in newly-weaned lambs improved growth performance, nutrient intake and nutrient digestibility reflected from better rumen fermentation and microbial parameters, blood metabolites and upregulation of growth and nutrient intake genes in the post-weaning lambs. |
| first_indexed | 2025-11-15T12:17:55Z |
| format | Article |
| id | upm-79614 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T12:17:55Z |
| publishDate | 2019 |
| publisher | BioMed Central |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-796142021-08-14T23:19:11Z http://psasir.upm.edu.my/id/eprint/79614/ Effects of postbiotic supplementation on growth performance, ruminal fermentation and microbial profile, blood metabolite and GHR, IGF-1 and MCT-1 gene expression in post-weaning lambs Wan Ibrahim, Izuddin Loh, Teck Chwen Samsudin, Anjas Asmara @ Ab Hadi Foo, Hooi Ling Merzza, Humam Ali Shazali, Nurhazirah Background: Postbiotics have been established as potential feed additive to be used in monogastric such as poultry and swine to enhance health and growth performance. However, information on the postbiotics as feed additive in ruminants is very limited. The aim of this study was to elucidate the effects of supplementation of postbiotics in newly-weaned lambs on growth performance, digestibility, rumen fermentation characteristics and microbial population, blood metabolite and expression of genes related to growth and volatile fatty acid transport across the rumen epithelium. Results: Postbiotic supplementation increased weight gain, feed intake, nutrient intake and nutrient digestibility of the lambs. No effect on ruminal pH and total VFA, whereas butyrate and ruminal ammonia-N concentration were improved. The lambs fed with postbiotics had higher blood total protein, urea nitrogen and glucose. However, no difference was observed in blood triglycerides and cholesterol levels. Postbiotics increased the population of fibre degrading bacteria but decreased total protozoa and methanogens in rumen. Postbiotics increased the mRNA expression of hepatic IGF-1 and ruminal MCT-1. Conclusions: The inclusion of postbiotics from L. plantarum RG14 in newly-weaned lambs improved growth performance, nutrient intake and nutrient digestibility reflected from better rumen fermentation and microbial parameters, blood metabolites and upregulation of growth and nutrient intake genes in the post-weaning lambs. BioMed Central 2019 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/79614/1/Effects%20of%20postbiotic%20supplementation%20on%20growth%20performance.pdf Wan Ibrahim, Izuddin and Loh, Teck Chwen and Samsudin, Anjas Asmara @ Ab Hadi and Foo, Hooi Ling and Merzza, Humam Ali and Shazali, Nurhazirah (2019) Effects of postbiotic supplementation on growth performance, ruminal fermentation and microbial profile, blood metabolite and GHR, IGF-1 and MCT-1 gene expression in post-weaning lambs. BMC Veterinary Research, 15. pp. 1-10. ISSN 1746-6148 https://bmcvetres.biomedcentral.com/articles/10.1186/s12917-019-2064-9 10.1186/s12917-019-2064-9 |
| spellingShingle | Wan Ibrahim, Izuddin Loh, Teck Chwen Samsudin, Anjas Asmara @ Ab Hadi Foo, Hooi Ling Merzza, Humam Ali Shazali, Nurhazirah Effects of postbiotic supplementation on growth performance, ruminal fermentation and microbial profile, blood metabolite and GHR, IGF-1 and MCT-1 gene expression in post-weaning lambs |
| title | Effects of postbiotic supplementation on growth performance, ruminal fermentation and microbial profile, blood metabolite and GHR, IGF-1 and MCT-1 gene expression in post-weaning lambs |
| title_full | Effects of postbiotic supplementation on growth performance, ruminal fermentation and microbial profile, blood metabolite and GHR, IGF-1 and MCT-1 gene expression in post-weaning lambs |
| title_fullStr | Effects of postbiotic supplementation on growth performance, ruminal fermentation and microbial profile, blood metabolite and GHR, IGF-1 and MCT-1 gene expression in post-weaning lambs |
| title_full_unstemmed | Effects of postbiotic supplementation on growth performance, ruminal fermentation and microbial profile, blood metabolite and GHR, IGF-1 and MCT-1 gene expression in post-weaning lambs |
| title_short | Effects of postbiotic supplementation on growth performance, ruminal fermentation and microbial profile, blood metabolite and GHR, IGF-1 and MCT-1 gene expression in post-weaning lambs |
| title_sort | effects of postbiotic supplementation on growth performance, ruminal fermentation and microbial profile, blood metabolite and ghr, igf-1 and mct-1 gene expression in post-weaning lambs |
| url | http://psasir.upm.edu.my/id/eprint/79614/ http://psasir.upm.edu.my/id/eprint/79614/ http://psasir.upm.edu.my/id/eprint/79614/ http://psasir.upm.edu.my/id/eprint/79614/1/Effects%20of%20postbiotic%20supplementation%20on%20growth%20performance.pdf |