BDMC33, a curcumin derivative suppresses inflammatory responses in macrophage-like cellular system: role of inhibition in NF-κB and MAPK signaling pathways

BDMC33, a curcumin derivative suppresses inflammatory responses in macrophage-like cellular system: role of inhibition in NF-κB and MAPK signaling pathways

Our preliminary screening has shown that curcumin derivative BDMC33 [2,6-bis(2,5-dimethoxybenzylidene)cyclohexanone] exerted promising nitric oxide inhibitory activity in activated macrophages. However, the molecular basis and mechanism for its pharmacological action is yet to be elucidated. The aim...

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Bibliographic Details
Main Authors: Lee, Ka Heng, Chow, Yuh Lit, Vidyadaran, Sharmili, Abas, Faridah, Mohammed Alitheen, Noorjahan Banu, Shaari, Khozirah, Israf Ali, Daud Ahmad, Lajis, Nordin, Ahmad, Syahida
Format: Article
Language:English
Published: MDPI 2012
Online Access:http://psasir.upm.edu.my/id/eprint/78007/
http://psasir.upm.edu.my/id/eprint/78007/1/78007.pdf

Internet

http://psasir.upm.edu.my/id/eprint/78007/
http://psasir.upm.edu.my/id/eprint/78007/1/78007.pdf

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