Comparative study of the antioxidant activities of some lipase-catayzed alkyl dihydrocaffeates synthesized in ionic liquid
The solubility limitations of phenolic acids in many lipidic environments are now greatly improved by their enzymatic esterification in ionic liquids (ILs). Herein, four different ILs were tested for the esterification of dihydrocaffeic acid with hexanol and the best IL was selected for the synthesi...
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| Format: | Article |
| Language: | English |
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Elsevier
2017
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| Online Access: | http://psasir.upm.edu.my/id/eprint/61167/ http://psasir.upm.edu.my/id/eprint/61167/1/Comparative%20study%20of%20the%20antioxidant%20activities%20of%20some%20lipase-catayzed%20alkyl%20dihydrocaffeates%20synthesized%20in%20ionic%20liquid.pdf |
| _version_ | 1848854354838159360 |
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| author | Gholivand, Somayeh Lasekan, Ola Tan, Chin Ping Abas, Faridah Leong, Sze Wei |
| author_facet | Gholivand, Somayeh Lasekan, Ola Tan, Chin Ping Abas, Faridah Leong, Sze Wei |
| author_sort | Gholivand, Somayeh |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | The solubility limitations of phenolic acids in many lipidic environments are now greatly improved by their enzymatic esterification in ionic liquids (ILs). Herein, four different ILs were tested for the esterification of dihydrocaffeic acid with hexanol and the best IL was selected for the synthesis of four other n-alkyl esters with different chain-lengths. The effect of alkyl chain length on the anti-oxidative properties of the resulted purified esters was investigated using β-carotene bleaching (BCB) and free radical scavenging method DPPH and compared with butylated hydroxytoluene (BHT) as reference compound. All four esters (methyl, hexyl, dodecyl and octadecyl dihydrocaffeates) exhibited relatively strong radical scavenging abilities. The scavenging activity of the test compounds was in the following order: methyl ester>hexyl ester⩾dodecyl ester>octadecyl ester>BHT while the order for the BCB anti-oxidative activity was; BHT>octadecyl ester>dodecyl ester>hexyl ester>methyl ester. |
| first_indexed | 2025-11-15T11:08:32Z |
| format | Article |
| id | upm-61167 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T11:08:32Z |
| publishDate | 2017 |
| publisher | Elsevier |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-611672018-09-13T02:37:09Z http://psasir.upm.edu.my/id/eprint/61167/ Comparative study of the antioxidant activities of some lipase-catayzed alkyl dihydrocaffeates synthesized in ionic liquid Gholivand, Somayeh Lasekan, Ola Tan, Chin Ping Abas, Faridah Leong, Sze Wei The solubility limitations of phenolic acids in many lipidic environments are now greatly improved by their enzymatic esterification in ionic liquids (ILs). Herein, four different ILs were tested for the esterification of dihydrocaffeic acid with hexanol and the best IL was selected for the synthesis of four other n-alkyl esters with different chain-lengths. The effect of alkyl chain length on the anti-oxidative properties of the resulted purified esters was investigated using β-carotene bleaching (BCB) and free radical scavenging method DPPH and compared with butylated hydroxytoluene (BHT) as reference compound. All four esters (methyl, hexyl, dodecyl and octadecyl dihydrocaffeates) exhibited relatively strong radical scavenging abilities. The scavenging activity of the test compounds was in the following order: methyl ester>hexyl ester⩾dodecyl ester>octadecyl ester>BHT while the order for the BCB anti-oxidative activity was; BHT>octadecyl ester>dodecyl ester>hexyl ester>methyl ester. Elsevier 2017 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/61167/1/Comparative%20study%20of%20the%20antioxidant%20activities%20of%20some%20lipase-catayzed%20alkyl%20dihydrocaffeates%20synthesized%20in%20ionic%20liquid.pdf Gholivand, Somayeh and Lasekan, Ola and Tan, Chin Ping and Abas, Faridah and Leong, Sze Wei (2017) Comparative study of the antioxidant activities of some lipase-catayzed alkyl dihydrocaffeates synthesized in ionic liquid. Food Chemistry, 224. pp. 365-371. ISSN 0308-8146 https://reader.elsevier.com/reader/sd/pii/S0308814616320969?token=75564673E6525995A89D14187CB9D42DEF9F16E732A6A97E925DC58386021A3F10B83D343D093FEC7734FD73683CB072 10.1016/j.foodchem.2016.12.075 |
| spellingShingle | Gholivand, Somayeh Lasekan, Ola Tan, Chin Ping Abas, Faridah Leong, Sze Wei Comparative study of the antioxidant activities of some lipase-catayzed alkyl dihydrocaffeates synthesized in ionic liquid |
| title | Comparative study of the antioxidant activities of some lipase-catayzed alkyl dihydrocaffeates synthesized in ionic liquid |
| title_full | Comparative study of the antioxidant activities of some lipase-catayzed alkyl dihydrocaffeates synthesized in ionic liquid |
| title_fullStr | Comparative study of the antioxidant activities of some lipase-catayzed alkyl dihydrocaffeates synthesized in ionic liquid |
| title_full_unstemmed | Comparative study of the antioxidant activities of some lipase-catayzed alkyl dihydrocaffeates synthesized in ionic liquid |
| title_short | Comparative study of the antioxidant activities of some lipase-catayzed alkyl dihydrocaffeates synthesized in ionic liquid |
| title_sort | comparative study of the antioxidant activities of some lipase-catayzed alkyl dihydrocaffeates synthesized in ionic liquid |
| url | http://psasir.upm.edu.my/id/eprint/61167/ http://psasir.upm.edu.my/id/eprint/61167/ http://psasir.upm.edu.my/id/eprint/61167/ http://psasir.upm.edu.my/id/eprint/61167/1/Comparative%20study%20of%20the%20antioxidant%20activities%20of%20some%20lipase-catayzed%20alkyl%20dihydrocaffeates%20synthesized%20in%20ionic%20liquid.pdf |