LC-ESI-Q-TOF-MS identification of porcine-specific peptide biomarker in cooked pork for halal authentication

Identifying pork adulteration in the mixture of meat is nearly impossible with the naked eye. Therefore, with the aid of modern technology, an authentication technique can be developed from various sample state which range from small to molecular level. The present research focused on protein-based...

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Main Authors: Zainal Abidin, Siti Aimi Sarah, Wan Jamaluddin, Wan Noor Faradalila, Karsani, Saiful Anuar, Ismail, Amin, Sazili, Awis Qurni
Format: Conference or Workshop Item
Language:English
Published: Halal Products Research Institute, Universiti Putra Malaysia 2014
Online Access:http://psasir.upm.edu.my/id/eprint/60504/
http://psasir.upm.edu.my/id/eprint/60504/1/Mihrec%205.pdf
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author Zainal Abidin, Siti Aimi Sarah
Wan Jamaluddin, Wan Noor Faradalila
Karsani, Saiful Anuar
Ismail, Amin
Sazili, Awis Qurni
author_facet Zainal Abidin, Siti Aimi Sarah
Wan Jamaluddin, Wan Noor Faradalila
Karsani, Saiful Anuar
Ismail, Amin
Sazili, Awis Qurni
author_sort Zainal Abidin, Siti Aimi Sarah
building UPM Institutional Repository
collection Online Access
description Identifying pork adulteration in the mixture of meat is nearly impossible with the naked eye. Therefore, with the aid of modern technology, an authentication technique can be developed from various sample state which range from small to molecular level. The present research focused on protein-based method as an approach to differentiate pork from beef, chevon and chicken. Instead of using DNA markers, species authentication using proteomics approach was chosen as the state-of-the-art technology offers high discriminating power and specificity. The purpose of this study was to determine porcine-specific peptide biomarker from thermally processed meat using liquid chromatography electrospray ionization quadrupole time of flight mass spectrometry (LC-ESI-Q-TOF-MS) in which the marker peptides were derived from the trypsin hydrolysis of myosin-4. A thorough investigation of LC-ESI-Q-TOF-MS data revealed two myosin-4 peptides at position 1450-1472 which demonstrated species-specific properties to porcine.
first_indexed 2025-11-15T11:06:18Z
format Conference or Workshop Item
id upm-60504
institution Universiti Putra Malaysia
institution_category Local University
language English
last_indexed 2025-11-15T11:06:18Z
publishDate 2014
publisher Halal Products Research Institute, Universiti Putra Malaysia
recordtype eprints
repository_type Digital Repository
spelling upm-605042018-06-07T06:24:20Z http://psasir.upm.edu.my/id/eprint/60504/ LC-ESI-Q-TOF-MS identification of porcine-specific peptide biomarker in cooked pork for halal authentication Zainal Abidin, Siti Aimi Sarah Wan Jamaluddin, Wan Noor Faradalila Karsani, Saiful Anuar Ismail, Amin Sazili, Awis Qurni Identifying pork adulteration in the mixture of meat is nearly impossible with the naked eye. Therefore, with the aid of modern technology, an authentication technique can be developed from various sample state which range from small to molecular level. The present research focused on protein-based method as an approach to differentiate pork from beef, chevon and chicken. Instead of using DNA markers, species authentication using proteomics approach was chosen as the state-of-the-art technology offers high discriminating power and specificity. The purpose of this study was to determine porcine-specific peptide biomarker from thermally processed meat using liquid chromatography electrospray ionization quadrupole time of flight mass spectrometry (LC-ESI-Q-TOF-MS) in which the marker peptides were derived from the trypsin hydrolysis of myosin-4. A thorough investigation of LC-ESI-Q-TOF-MS data revealed two myosin-4 peptides at position 1450-1472 which demonstrated species-specific properties to porcine. Halal Products Research Institute, Universiti Putra Malaysia 2014 Conference or Workshop Item PeerReviewed text en http://psasir.upm.edu.my/id/eprint/60504/1/Mihrec%205.pdf Zainal Abidin, Siti Aimi Sarah and Wan Jamaluddin, Wan Noor Faradalila and Karsani, Saiful Anuar and Ismail, Amin and Sazili, Awis Qurni (2014) LC-ESI-Q-TOF-MS identification of porcine-specific peptide biomarker in cooked pork for halal authentication. In: Malaysia International Halal Research & Education Conference 2014 (MIHREC 2014), 2-4 Dec. 2014, Marriott Putrajaya Hotel, Malaysia. (pp. 47-52).
spellingShingle Zainal Abidin, Siti Aimi Sarah
Wan Jamaluddin, Wan Noor Faradalila
Karsani, Saiful Anuar
Ismail, Amin
Sazili, Awis Qurni
LC-ESI-Q-TOF-MS identification of porcine-specific peptide biomarker in cooked pork for halal authentication
title LC-ESI-Q-TOF-MS identification of porcine-specific peptide biomarker in cooked pork for halal authentication
title_full LC-ESI-Q-TOF-MS identification of porcine-specific peptide biomarker in cooked pork for halal authentication
title_fullStr LC-ESI-Q-TOF-MS identification of porcine-specific peptide biomarker in cooked pork for halal authentication
title_full_unstemmed LC-ESI-Q-TOF-MS identification of porcine-specific peptide biomarker in cooked pork for halal authentication
title_short LC-ESI-Q-TOF-MS identification of porcine-specific peptide biomarker in cooked pork for halal authentication
title_sort lc-esi-q-tof-ms identification of porcine-specific peptide biomarker in cooked pork for halal authentication
url http://psasir.upm.edu.my/id/eprint/60504/
http://psasir.upm.edu.my/id/eprint/60504/1/Mihrec%205.pdf