Prevalence, factors influencing and knowledge about adherence to lipid-lowering therapy among hyperlipidemia patients
Background: Hyperlipidaemia is a significant risk factor for cardiovascular disease. However, adherence to lipid-lowering therapy is often unsatisfactory due to a combination of patient factors, therapy, socio-economic and health system-related factors. Aims: to identify the prevalence of adherenc...
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| Format: | Article |
| Language: | English |
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Malaysian Medical Association
2017
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| Online Access: | http://psasir.upm.edu.my/id/eprint/56859/ http://psasir.upm.edu.my/id/eprint/56859/1/Prevalence%2C%20factors%20influencing%20and%20knowledge%20about%20adherence%20to%20lipid-lowering%20therapy%20among%20hyperlipidemia%20patients.pdf |
| _version_ | 1848853203545751552 |
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| author | Devaraj, Navin Kumar Mohamed, Mohazmi Hussein, Norita |
| author_facet | Devaraj, Navin Kumar Mohamed, Mohazmi Hussein, Norita |
| author_sort | Devaraj, Navin Kumar |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Background: Hyperlipidaemia is a significant risk factor for cardiovascular disease. However, adherence to lipid-lowering therapy is often unsatisfactory due to a combination of patient factors, therapy, socio-economic and health system-related factors.
Aims: to identify the prevalence of adherence to lipid-lowering therapy, the factors contributing to non-adherence and knowledge regarding hyperlipidaemia and its’ treatment among Malaysian patients with hyperlipidemia.
Methods: A quantitative study using a cross-sectional survey was carried out in an urban primary care clinic in August 2015. Patients on lipid-lowering therapy for ≥ 1 year aged ≥ 18 years were selected using simple random sampling. consenting patients answered a self-administered questionnaire (in Malay/English) which included socio-demographic profile, hyperlipidaemia profile, adherence to lipid-lowering therapy (using the Morisky Medication Adherence scale-8; score ≥ 6 taken as adherent), reasons leading to non-adherence, knowledge regarding hyperlipidaemia and its’ treatment, and use of non-allopathic medicine.
Results: the response rate was 90.7%. the prevalence of adherence to lipid-lowering therapy was 82.4%. “the most common reasons for non-adherence was being worried about side effect of lipid-lowering agent (71.4%), followed by the need to take too many drugs in a day (61.4%) and negative influences by friends, relative and mass media (60%)”. Factors associated with non-adherence include male gender, on longer duration of therapy, less frequency of follow-up, less number of follow-up clinics, taking medication at night/random timing and having lower knowledge scores.
Conclusion: Overall the prevalence of adherence was high in patients with hyperlipidaemia. Interventions to boost adherence should target those who were identified as non-adherent. |
| first_indexed | 2025-11-15T10:50:14Z |
| format | Article |
| id | upm-56859 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T10:50:14Z |
| publishDate | 2017 |
| publisher | Malaysian Medical Association |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-568592017-09-05T10:05:48Z http://psasir.upm.edu.my/id/eprint/56859/ Prevalence, factors influencing and knowledge about adherence to lipid-lowering therapy among hyperlipidemia patients Devaraj, Navin Kumar Mohamed, Mohazmi Hussein, Norita Background: Hyperlipidaemia is a significant risk factor for cardiovascular disease. However, adherence to lipid-lowering therapy is often unsatisfactory due to a combination of patient factors, therapy, socio-economic and health system-related factors. Aims: to identify the prevalence of adherence to lipid-lowering therapy, the factors contributing to non-adherence and knowledge regarding hyperlipidaemia and its’ treatment among Malaysian patients with hyperlipidemia. Methods: A quantitative study using a cross-sectional survey was carried out in an urban primary care clinic in August 2015. Patients on lipid-lowering therapy for ≥ 1 year aged ≥ 18 years were selected using simple random sampling. consenting patients answered a self-administered questionnaire (in Malay/English) which included socio-demographic profile, hyperlipidaemia profile, adherence to lipid-lowering therapy (using the Morisky Medication Adherence scale-8; score ≥ 6 taken as adherent), reasons leading to non-adherence, knowledge regarding hyperlipidaemia and its’ treatment, and use of non-allopathic medicine. Results: the response rate was 90.7%. the prevalence of adherence to lipid-lowering therapy was 82.4%. “the most common reasons for non-adherence was being worried about side effect of lipid-lowering agent (71.4%), followed by the need to take too many drugs in a day (61.4%) and negative influences by friends, relative and mass media (60%)”. Factors associated with non-adherence include male gender, on longer duration of therapy, less frequency of follow-up, less number of follow-up clinics, taking medication at night/random timing and having lower knowledge scores. Conclusion: Overall the prevalence of adherence was high in patients with hyperlipidaemia. Interventions to boost adherence should target those who were identified as non-adherent. Malaysian Medical Association 2017 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/56859/1/Prevalence%2C%20factors%20influencing%20and%20knowledge%20about%20adherence%20to%20lipid-lowering%20therapy%20among%20hyperlipidemia%20patients.pdf Devaraj, Navin Kumar and Mohamed, Mohazmi and Hussein, Norita (2017) Prevalence, factors influencing and knowledge about adherence to lipid-lowering therapy among hyperlipidemia patients. Medical Journal of Malaysia, 72 (3). pp. 157-164. ISSN 0300-5283 http://www.e-mjm.org/index.html |
| spellingShingle | Devaraj, Navin Kumar Mohamed, Mohazmi Hussein, Norita Prevalence, factors influencing and knowledge about adherence to lipid-lowering therapy among hyperlipidemia patients |
| title | Prevalence, factors influencing and knowledge about adherence to lipid-lowering therapy among hyperlipidemia patients |
| title_full | Prevalence, factors influencing and knowledge about adherence to lipid-lowering therapy among hyperlipidemia patients |
| title_fullStr | Prevalence, factors influencing and knowledge about adherence to lipid-lowering therapy among hyperlipidemia patients |
| title_full_unstemmed | Prevalence, factors influencing and knowledge about adherence to lipid-lowering therapy among hyperlipidemia patients |
| title_short | Prevalence, factors influencing and knowledge about adherence to lipid-lowering therapy among hyperlipidemia patients |
| title_sort | prevalence, factors influencing and knowledge about adherence to lipid-lowering therapy among hyperlipidemia patients |
| url | http://psasir.upm.edu.my/id/eprint/56859/ http://psasir.upm.edu.my/id/eprint/56859/ http://psasir.upm.edu.my/id/eprint/56859/1/Prevalence%2C%20factors%20influencing%20and%20knowledge%20about%20adherence%20to%20lipid-lowering%20therapy%20among%20hyperlipidemia%20patients.pdf |