Kojic acid esters: comparative review on its methods of synthesis

In this paper, the syntheses of kojic acid esters via chemical and enzymatic methods are reviewed. The advantages and disadvantages of chemical process in term of process, safety and efficiency are discussed. In enzymatic process, the significant process parameters related to the synthesis of kojic...

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Main Authors: Ishak, Nurazwa, Lajis, Ahmad Firdaus, Mohamad, Rosfarizan, Ariff, Arbakariya, Halim, Murni, Wasoh @ Mohamad Isa, Helmi
Format: Article
Language:English
Published: Hibiscus Publisher 2016
Online Access:http://psasir.upm.edu.my/id/eprint/54683/
http://psasir.upm.edu.my/id/eprint/54683/1/Kojic%20acid%20esters.pdf
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author Ishak, Nurazwa
Lajis, Ahmad Firdaus
Mohamad, Rosfarizan
Ariff, Arbakariya
Halim, Murni
Wasoh @ Mohamad Isa, Helmi
author_facet Ishak, Nurazwa
Lajis, Ahmad Firdaus
Mohamad, Rosfarizan
Ariff, Arbakariya
Halim, Murni
Wasoh @ Mohamad Isa, Helmi
author_sort Ishak, Nurazwa
building UPM Institutional Repository
collection Online Access
description In this paper, the syntheses of kojic acid esters via chemical and enzymatic methods are reviewed. The advantages and disadvantages of chemical process in term of process, safety and efficiency are discussed. In enzymatic process, the significant process parameters related to the synthesis of kojic acid esters such as the lipases, solvent, temperature and water content are highlighted. Possible enzymatic synthesis using solvent and solvent-free system taking into consideration of the difference in these systems involving cost, lipase reusability and efficiency is comparatively reviewed. The possible approach for large scale production using various enzyme reactor designs is also discussed and re-evaluated.
first_indexed 2025-11-15T10:40:46Z
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institution Universiti Putra Malaysia
institution_category Local University
language English
last_indexed 2025-11-15T10:40:46Z
publishDate 2016
publisher Hibiscus Publisher
recordtype eprints
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spelling upm-546832018-04-19T01:47:57Z http://psasir.upm.edu.my/id/eprint/54683/ Kojic acid esters: comparative review on its methods of synthesis Ishak, Nurazwa Lajis, Ahmad Firdaus Mohamad, Rosfarizan Ariff, Arbakariya Halim, Murni Wasoh @ Mohamad Isa, Helmi In this paper, the syntheses of kojic acid esters via chemical and enzymatic methods are reviewed. The advantages and disadvantages of chemical process in term of process, safety and efficiency are discussed. In enzymatic process, the significant process parameters related to the synthesis of kojic acid esters such as the lipases, solvent, temperature and water content are highlighted. Possible enzymatic synthesis using solvent and solvent-free system taking into consideration of the difference in these systems involving cost, lipase reusability and efficiency is comparatively reviewed. The possible approach for large scale production using various enzyme reactor designs is also discussed and re-evaluated. Hibiscus Publisher 2016 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/54683/1/Kojic%20acid%20esters.pdf Ishak, Nurazwa and Lajis, Ahmad Firdaus and Mohamad, Rosfarizan and Ariff, Arbakariya and Halim, Murni and Wasoh @ Mohamad Isa, Helmi (2016) Kojic acid esters: comparative review on its methods of synthesis. Journal of Biochemistry, Microbiology and Biotechnology, 4 (2). pp. 7-15. ISSN 2289-5779 https://journal.hibiscuspublisher.com/index.php/JOBIMB/article/view/304
spellingShingle Ishak, Nurazwa
Lajis, Ahmad Firdaus
Mohamad, Rosfarizan
Ariff, Arbakariya
Halim, Murni
Wasoh @ Mohamad Isa, Helmi
Kojic acid esters: comparative review on its methods of synthesis
title Kojic acid esters: comparative review on its methods of synthesis
title_full Kojic acid esters: comparative review on its methods of synthesis
title_fullStr Kojic acid esters: comparative review on its methods of synthesis
title_full_unstemmed Kojic acid esters: comparative review on its methods of synthesis
title_short Kojic acid esters: comparative review on its methods of synthesis
title_sort kojic acid esters: comparative review on its methods of synthesis
url http://psasir.upm.edu.my/id/eprint/54683/
http://psasir.upm.edu.my/id/eprint/54683/
http://psasir.upm.edu.my/id/eprint/54683/1/Kojic%20acid%20esters.pdf