16S metagenomic microbial composition analysis of kefir grain using MEGAN and BaseSpace

Kefir is a unique cultured product traditionally made from the fermentation of milk with kefir grains. Metagenomics analysis of kefir grain is essential to understand the composition of microbial populations in the kefir grain. Many microbial populations have been reported in kefir grains from diffe...

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Main Authors: Zamberi, Nur Rizi, Mohamad, Nurul Elyani, Yeap, Swee Keong, Ky, Huynh, Beh, Boon Kee, Liew, Woan Charn, Tan, Sheau Wei, Ho, Wan Yong, Boo, Sook Yee, Chua, Yi Heng, Mohammed Alitheen, Noorjahan Banu
Format: Article
Language:English
Published: Taylor & Francis 2016
Online Access:http://psasir.upm.edu.my/id/eprint/52110/
http://psasir.upm.edu.my/id/eprint/52110/1/16S%20metagenomic%20microbial%20composition%20analysis%20of%20kefir%20grain%20using%20MEGAN%20and%20BaseSpace.pdf
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author Zamberi, Nur Rizi
Mohamad, Nurul Elyani
Yeap, Swee Keong
Ky, Huynh
Beh, Boon Kee
Liew, Woan Charn
Tan, Sheau Wei
Ho, Wan Yong
Boo, Sook Yee
Chua, Yi Heng
Mohammed Alitheen, Noorjahan Banu
author_facet Zamberi, Nur Rizi
Mohamad, Nurul Elyani
Yeap, Swee Keong
Ky, Huynh
Beh, Boon Kee
Liew, Woan Charn
Tan, Sheau Wei
Ho, Wan Yong
Boo, Sook Yee
Chua, Yi Heng
Mohammed Alitheen, Noorjahan Banu
author_sort Zamberi, Nur Rizi
building UPM Institutional Repository
collection Online Access
description Kefir is a unique cultured product traditionally made from the fermentation of milk with kefir grains. Metagenomics analysis of kefir grain is essential to understand the composition of microbial populations in the kefir grain. Many microbial populations have been reported in kefir grains from different parts of the world. Although the kefir from Malaysian kefir grain is regularly consumed locally, no report has been made on the kefir grain microbial profile. The present study used kefir grain obtained locally and the microbial composition in the kefir grain was determined using Next Generation Sequencing (NGS). The taxonomic results analysis obtained when using BaseSpace (Illumina) and MEGAN were compared. The software agreed that Lactobacillus genus dominated the samples and the predominant species was L. kefiranofaciens (81.45–91.93%) while L. kefiri (2.01–2.47%) was the second in abundance. The results suggested that Malaysian kefir grain contained the same top two predominant species using both software methods and the microbial composition between both software did not vary significantly.
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publisher Taylor & Francis
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spelling upm-521102017-05-05T02:58:17Z http://psasir.upm.edu.my/id/eprint/52110/ 16S metagenomic microbial composition analysis of kefir grain using MEGAN and BaseSpace Zamberi, Nur Rizi Mohamad, Nurul Elyani Yeap, Swee Keong Ky, Huynh Beh, Boon Kee Liew, Woan Charn Tan, Sheau Wei Ho, Wan Yong Boo, Sook Yee Chua, Yi Heng Mohammed Alitheen, Noorjahan Banu Kefir is a unique cultured product traditionally made from the fermentation of milk with kefir grains. Metagenomics analysis of kefir grain is essential to understand the composition of microbial populations in the kefir grain. Many microbial populations have been reported in kefir grains from different parts of the world. Although the kefir from Malaysian kefir grain is regularly consumed locally, no report has been made on the kefir grain microbial profile. The present study used kefir grain obtained locally and the microbial composition in the kefir grain was determined using Next Generation Sequencing (NGS). The taxonomic results analysis obtained when using BaseSpace (Illumina) and MEGAN were compared. The software agreed that Lactobacillus genus dominated the samples and the predominant species was L. kefiranofaciens (81.45–91.93%) while L. kefiri (2.01–2.47%) was the second in abundance. The results suggested that Malaysian kefir grain contained the same top two predominant species using both software methods and the microbial composition between both software did not vary significantly. Taylor & Francis 2016 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/52110/1/16S%20metagenomic%20microbial%20composition%20analysis%20of%20kefir%20grain%20using%20MEGAN%20and%20BaseSpace.pdf Zamberi, Nur Rizi and Mohamad, Nurul Elyani and Yeap, Swee Keong and Ky, Huynh and Beh, Boon Kee and Liew, Woan Charn and Tan, Sheau Wei and Ho, Wan Yong and Boo, Sook Yee and Chua, Yi Heng and Mohammed Alitheen, Noorjahan Banu (2016) 16S metagenomic microbial composition analysis of kefir grain using MEGAN and BaseSpace. Food Biotechnology, 30 (3). pp. 219-230. ISSN 0890-5436; ESSN: 1532-4249 http://www.tandfonline.com/doi/abs/10.1080/08905436.2016.1200987?journalCode=lfbt20 10.1080/08905436.2016.1200987
spellingShingle Zamberi, Nur Rizi
Mohamad, Nurul Elyani
Yeap, Swee Keong
Ky, Huynh
Beh, Boon Kee
Liew, Woan Charn
Tan, Sheau Wei
Ho, Wan Yong
Boo, Sook Yee
Chua, Yi Heng
Mohammed Alitheen, Noorjahan Banu
16S metagenomic microbial composition analysis of kefir grain using MEGAN and BaseSpace
title 16S metagenomic microbial composition analysis of kefir grain using MEGAN and BaseSpace
title_full 16S metagenomic microbial composition analysis of kefir grain using MEGAN and BaseSpace
title_fullStr 16S metagenomic microbial composition analysis of kefir grain using MEGAN and BaseSpace
title_full_unstemmed 16S metagenomic microbial composition analysis of kefir grain using MEGAN and BaseSpace
title_short 16S metagenomic microbial composition analysis of kefir grain using MEGAN and BaseSpace
title_sort 16s metagenomic microbial composition analysis of kefir grain using megan and basespace
url http://psasir.upm.edu.my/id/eprint/52110/
http://psasir.upm.edu.my/id/eprint/52110/
http://psasir.upm.edu.my/id/eprint/52110/
http://psasir.upm.edu.my/id/eprint/52110/1/16S%20metagenomic%20microbial%20composition%20analysis%20of%20kefir%20grain%20using%20MEGAN%20and%20BaseSpace.pdf