Prevalence of dyslipidaemia in type 2 diabetes mellitus patients and its association to diabetic retinopathy in a Malaysian tertiary hospital
Background: Diabetic retinopathy (DR) is a microvascular complication of diabetes, which is a cause of visual impairment and blindness. Its development and progression have been linked to dyslipidaemia, although the link remains inconclusive. Aim: This study aimed to determine the prevalence of dysl...
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| Format: | Article |
| Language: | English |
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Faculty of Medicine and Health Sciences, Universiti Putra Malaysia
2014
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| Online Access: | http://psasir.upm.edu.my/id/eprint/41422/ http://psasir.upm.edu.my/id/eprint/41422/1/Prevalence%20of%20dyslipidaemia%20in%20type%202%20diabetes%20mellitus%20patients%20and%20its%20association%20to%20diabetic%20retinopathy%20in%20a%20Malaysian%20tertiary%20hospital.pdf |
| _version_ | 1848849690789937152 |
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| author | Samsudin, Intan Nureslyna Md Saleh, Rafidah Chellappah Thambiah, Subashini Mohamad Amir Hamzah, Aiffa Syafira Wan Khalik, Wan Noor Fatini George, Elizabeth |
| author_facet | Samsudin, Intan Nureslyna Md Saleh, Rafidah Chellappah Thambiah, Subashini Mohamad Amir Hamzah, Aiffa Syafira Wan Khalik, Wan Noor Fatini George, Elizabeth |
| author_sort | Samsudin, Intan Nureslyna |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Background: Diabetic retinopathy (DR) is a microvascular complication of diabetes, which is a cause of visual impairment and blindness. Its development and progression have been linked to dyslipidaemia, although the link remains inconclusive. Aim: This study aimed to determine the prevalence of dyslipidaemia among type 2 diabetic patients with DR in a tertiary setting and to determine the association between dyslipidaemia and DR severity. Materials and methods: This was a cross sectional study using retrospective data of type 2 diabetic patients attending the opthalmology clinic of a tertiary centre from
January 2007 to June 2014. Results of their fasting lipid profile and clinical data were retrieved from the hospital information system. Results: A total of 178 patient’s data were collected. 120 (n=67.4%) patients had non-proliferative diabetic retinopathy (NDPR) with moderate NPDR being the most prevalent. Dyslipidaemia was noted in 151 (84.8%) of the patients. Patients had a combination of more than one abnormality in the lipid profile with increased LDL-cholesterol being the main abnormality. Dyslipidaemia was however, not significantly associated with DR severity. Conclusion: Dyslipidaemia was highly prevalent in DR patients. The dyslipidaemia was however not associated with severity of DR. |
| first_indexed | 2025-11-15T09:54:24Z |
| format | Article |
| id | upm-41422 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T09:54:24Z |
| publishDate | 2014 |
| publisher | Faculty of Medicine and Health Sciences, Universiti Putra Malaysia |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-414222015-12-18T03:36:30Z http://psasir.upm.edu.my/id/eprint/41422/ Prevalence of dyslipidaemia in type 2 diabetes mellitus patients and its association to diabetic retinopathy in a Malaysian tertiary hospital Samsudin, Intan Nureslyna Md Saleh, Rafidah Chellappah Thambiah, Subashini Mohamad Amir Hamzah, Aiffa Syafira Wan Khalik, Wan Noor Fatini George, Elizabeth Background: Diabetic retinopathy (DR) is a microvascular complication of diabetes, which is a cause of visual impairment and blindness. Its development and progression have been linked to dyslipidaemia, although the link remains inconclusive. Aim: This study aimed to determine the prevalence of dyslipidaemia among type 2 diabetic patients with DR in a tertiary setting and to determine the association between dyslipidaemia and DR severity. Materials and methods: This was a cross sectional study using retrospective data of type 2 diabetic patients attending the opthalmology clinic of a tertiary centre from January 2007 to June 2014. Results of their fasting lipid profile and clinical data were retrieved from the hospital information system. Results: A total of 178 patient’s data were collected. 120 (n=67.4%) patients had non-proliferative diabetic retinopathy (NDPR) with moderate NPDR being the most prevalent. Dyslipidaemia was noted in 151 (84.8%) of the patients. Patients had a combination of more than one abnormality in the lipid profile with increased LDL-cholesterol being the main abnormality. Dyslipidaemia was however, not significantly associated with DR severity. Conclusion: Dyslipidaemia was highly prevalent in DR patients. The dyslipidaemia was however not associated with severity of DR. Faculty of Medicine and Health Sciences, Universiti Putra Malaysia 2014-06 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/41422/1/Prevalence%20of%20dyslipidaemia%20in%20type%202%20diabetes%20mellitus%20patients%20and%20its%20association%20to%20diabetic%20retinopathy%20in%20a%20Malaysian%20tertiary%20hospital.pdf Samsudin, Intan Nureslyna and Md Saleh, Rafidah and Chellappah Thambiah, Subashini and Mohamad Amir Hamzah, Aiffa Syafira and Wan Khalik, Wan Noor Fatini and George, Elizabeth (2014) Prevalence of dyslipidaemia in type 2 diabetes mellitus patients and its association to diabetic retinopathy in a Malaysian tertiary hospital. Malaysian Journal of Medicine and Health Sciences, 10 (2). pp. 47-51. ISSN 1675-8544 http://www.medic.upm.edu.my/dokumen/FKUSK1_Jurnal_Text_Article_6.pdf |
| spellingShingle | Samsudin, Intan Nureslyna Md Saleh, Rafidah Chellappah Thambiah, Subashini Mohamad Amir Hamzah, Aiffa Syafira Wan Khalik, Wan Noor Fatini George, Elizabeth Prevalence of dyslipidaemia in type 2 diabetes mellitus patients and its association to diabetic retinopathy in a Malaysian tertiary hospital |
| title | Prevalence of dyslipidaemia in type 2 diabetes mellitus patients and its association to diabetic retinopathy in a Malaysian tertiary hospital |
| title_full | Prevalence of dyslipidaemia in type 2 diabetes mellitus patients and its association to diabetic retinopathy in a Malaysian tertiary hospital |
| title_fullStr | Prevalence of dyslipidaemia in type 2 diabetes mellitus patients and its association to diabetic retinopathy in a Malaysian tertiary hospital |
| title_full_unstemmed | Prevalence of dyslipidaemia in type 2 diabetes mellitus patients and its association to diabetic retinopathy in a Malaysian tertiary hospital |
| title_short | Prevalence of dyslipidaemia in type 2 diabetes mellitus patients and its association to diabetic retinopathy in a Malaysian tertiary hospital |
| title_sort | prevalence of dyslipidaemia in type 2 diabetes mellitus patients and its association to diabetic retinopathy in a malaysian tertiary hospital |
| url | http://psasir.upm.edu.my/id/eprint/41422/ http://psasir.upm.edu.my/id/eprint/41422/ http://psasir.upm.edu.my/id/eprint/41422/1/Prevalence%20of%20dyslipidaemia%20in%20type%202%20diabetes%20mellitus%20patients%20and%20its%20association%20to%20diabetic%20retinopathy%20in%20a%20Malaysian%20tertiary%20hospital.pdf |