Sargassum seaweed as a source of anti-inflammatory substances and the potential insight of the tropical species: a review
Sargassum is recognized both empirically and scientifically as a potential anti-inflammatory agent. Inflammation is an important response in the body that helps to overcome various challenges to body homeostasis such as microbial infections, tissue stress, and certain injuries. Excessive and uncontr...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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MDPI
2019
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| Online Access: | http://psasir.upm.edu.my/id/eprint/38233/ http://psasir.upm.edu.my/id/eprint/38233/1/38233.pdf |
| _version_ | 1848848822645555200 |
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| author | Saraswati Giriwono, Puspo Edi Iskandriati, Diah Tan, Chin Ping Andarwulan, Nuri |
| author_facet | Saraswati Giriwono, Puspo Edi Iskandriati, Diah Tan, Chin Ping Andarwulan, Nuri |
| author_sort | Saraswati |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Sargassum is recognized both empirically and scientifically as a potential anti-inflammatory agent. Inflammation is an important response in the body that helps to overcome various challenges to body homeostasis such as microbial infections, tissue stress, and certain injuries. Excessive and uncontrolled inflammatory conditions can affect the pathogenesis of various diseases. This review aims to explore the potential of Sargassum’s anti-inflammatory activity, not only in crude extracts but also in sulfated polysaccharides and purified compounds. The tropical region has a promising availability of Sargassum biomass because its climate allows for the optimal growth of seaweed throughout the year. This is important for its commercial utilization as functional ingredients for both food and non-food applications. To the best of our knowledge, studies related to Sargassum’s anti-inflammatory activity are still dominated by subtropical species. Studies on tropical Sargassum are mainly focused on the polysaccharides group, though there are some other potentially bioactive compounds such as polyphenols, terpenoids, fucoxanthin, fatty acids and their derivatives, typical polar lipids, and other groups. Information on the modulation mechanism of Sargassum’s bioactive compounds on the inflammatory response is also discussed here, but specific mechanisms related to the interaction between bioactive compounds and targets in cells still need to be further studied. |
| first_indexed | 2025-11-15T09:40:37Z |
| format | Article |
| id | upm-38233 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T09:40:37Z |
| publishDate | 2019 |
| publisher | MDPI |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-382332020-05-04T16:04:06Z http://psasir.upm.edu.my/id/eprint/38233/ Sargassum seaweed as a source of anti-inflammatory substances and the potential insight of the tropical species: a review Saraswati Giriwono, Puspo Edi Iskandriati, Diah Tan, Chin Ping Andarwulan, Nuri Sargassum is recognized both empirically and scientifically as a potential anti-inflammatory agent. Inflammation is an important response in the body that helps to overcome various challenges to body homeostasis such as microbial infections, tissue stress, and certain injuries. Excessive and uncontrolled inflammatory conditions can affect the pathogenesis of various diseases. This review aims to explore the potential of Sargassum’s anti-inflammatory activity, not only in crude extracts but also in sulfated polysaccharides and purified compounds. The tropical region has a promising availability of Sargassum biomass because its climate allows for the optimal growth of seaweed throughout the year. This is important for its commercial utilization as functional ingredients for both food and non-food applications. To the best of our knowledge, studies related to Sargassum’s anti-inflammatory activity are still dominated by subtropical species. Studies on tropical Sargassum are mainly focused on the polysaccharides group, though there are some other potentially bioactive compounds such as polyphenols, terpenoids, fucoxanthin, fatty acids and their derivatives, typical polar lipids, and other groups. Information on the modulation mechanism of Sargassum’s bioactive compounds on the inflammatory response is also discussed here, but specific mechanisms related to the interaction between bioactive compounds and targets in cells still need to be further studied. MDPI 2019 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/38233/1/38233.pdf Saraswati and Giriwono, Puspo Edi and Iskandriati, Diah and Tan, Chin Ping and Andarwulan, Nuri (2019) Sargassum seaweed as a source of anti-inflammatory substances and the potential insight of the tropical species: a review. Marine Drugs, 17 (10). art. no. 590. pp. 1-35. ISSN 1660-3397 https://www.mdpi.com/1660-3397/17/10/590 10.3390/md17100590 |
| spellingShingle | Saraswati Giriwono, Puspo Edi Iskandriati, Diah Tan, Chin Ping Andarwulan, Nuri Sargassum seaweed as a source of anti-inflammatory substances and the potential insight of the tropical species: a review |
| title | Sargassum seaweed as a source of anti-inflammatory substances and the potential insight of the tropical species: a review |
| title_full | Sargassum seaweed as a source of anti-inflammatory substances and the potential insight of the tropical species: a review |
| title_fullStr | Sargassum seaweed as a source of anti-inflammatory substances and the potential insight of the tropical species: a review |
| title_full_unstemmed | Sargassum seaweed as a source of anti-inflammatory substances and the potential insight of the tropical species: a review |
| title_short | Sargassum seaweed as a source of anti-inflammatory substances and the potential insight of the tropical species: a review |
| title_sort | sargassum seaweed as a source of anti-inflammatory substances and the potential insight of the tropical species: a review |
| url | http://psasir.upm.edu.my/id/eprint/38233/ http://psasir.upm.edu.my/id/eprint/38233/ http://psasir.upm.edu.my/id/eprint/38233/ http://psasir.upm.edu.my/id/eprint/38233/1/38233.pdf |