Histopathology and immunohistochemistry assessments of acute experimental infection by Brucella melitensis in bucks
Brucellosis in male goats is characterized by arthritis, orchitis and epididymitis, which may induce infertility. Nevertheless, these lesions were categorized as chronic while acute lesions had not been described. This study investigates the histopathological and immuno histochemistry reactions in o...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Scientific Research Publishing
2014
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| Online Access: | http://psasir.upm.edu.my/id/eprint/37871/ http://psasir.upm.edu.my/id/eprint/37871/1/Histopathology%20and%20immunohistochemistry%20assessments%20of%20acute%20experimental%20infection%20by%20Brucella%20melitensis%20in%20bucks.pdf |
| _version_ | 1848848723025592320 |
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| author | Nasruddin, Nurrul Shaqinah Mazlan, Mazlina Saad, Mohd Zamri Hamzah, Hazilawati Sabri, Jasni |
| author_facet | Nasruddin, Nurrul Shaqinah Mazlan, Mazlina Saad, Mohd Zamri Hamzah, Hazilawati Sabri, Jasni |
| author_sort | Nasruddin, Nurrul Shaqinah |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Brucellosis in male goats is characterized by arthritis, orchitis and epididymitis, which may induce infertility. Nevertheless, these lesions were categorized as chronic while acute lesions had not been described. This study investigates the histopathological and immuno histochemistry reactions in organs of bucks acutely infected by Brucella melitensis. Results: Only testis and prepuce of acutely infected bucks showed significantly severe histological lesions. Other internal organs had mild to moderate lesions. However, positive immunohistochemistry stainings were observed in organs except the bulbourethral gland. There was a significant positive correlation between the distribution of B. melitensis and IHC intensity but no significant correlation between the IHC intensity and histopathology lesions. Conclusion: The results indicate that acute brucellosis did not lead to clinical presentation, although B. melitensis was well distributed in various organs of bucks. |
| first_indexed | 2025-11-15T09:39:02Z |
| format | Article |
| id | upm-37871 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T09:39:02Z |
| publishDate | 2014 |
| publisher | Scientific Research Publishing |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-378712015-12-03T06:53:27Z http://psasir.upm.edu.my/id/eprint/37871/ Histopathology and immunohistochemistry assessments of acute experimental infection by Brucella melitensis in bucks Nasruddin, Nurrul Shaqinah Mazlan, Mazlina Saad, Mohd Zamri Hamzah, Hazilawati Sabri, Jasni Brucellosis in male goats is characterized by arthritis, orchitis and epididymitis, which may induce infertility. Nevertheless, these lesions were categorized as chronic while acute lesions had not been described. This study investigates the histopathological and immuno histochemistry reactions in organs of bucks acutely infected by Brucella melitensis. Results: Only testis and prepuce of acutely infected bucks showed significantly severe histological lesions. Other internal organs had mild to moderate lesions. However, positive immunohistochemistry stainings were observed in organs except the bulbourethral gland. There was a significant positive correlation between the distribution of B. melitensis and IHC intensity but no significant correlation between the IHC intensity and histopathology lesions. Conclusion: The results indicate that acute brucellosis did not lead to clinical presentation, although B. melitensis was well distributed in various organs of bucks. Scientific Research Publishing 2014-04 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/37871/1/Histopathology%20and%20immunohistochemistry%20assessments%20of%20acute%20experimental%20infection%20by%20Brucella%20melitensis%20in%20bucks.pdf Nasruddin, Nurrul Shaqinah and Mazlan, Mazlina and Saad, Mohd Zamri and Hamzah, Hazilawati and Sabri, Jasni (2014) Histopathology and immunohistochemistry assessments of acute experimental infection by Brucella melitensis in bucks. Open Journal of Pathology, 4 (2). pp. 54-63. ISSN 2164-6775; ESSN: 2164-6783 http://www.scirp.org/journal/PaperInformation.aspx?PaperID=45220 10.4236/ojpathology.2014.42009 |
| spellingShingle | Nasruddin, Nurrul Shaqinah Mazlan, Mazlina Saad, Mohd Zamri Hamzah, Hazilawati Sabri, Jasni Histopathology and immunohistochemistry assessments of acute experimental infection by Brucella melitensis in bucks |
| title | Histopathology and immunohistochemistry assessments of acute experimental infection by Brucella melitensis in bucks |
| title_full | Histopathology and immunohistochemistry assessments of acute experimental infection by Brucella melitensis in bucks |
| title_fullStr | Histopathology and immunohistochemistry assessments of acute experimental infection by Brucella melitensis in bucks |
| title_full_unstemmed | Histopathology and immunohistochemistry assessments of acute experimental infection by Brucella melitensis in bucks |
| title_short | Histopathology and immunohistochemistry assessments of acute experimental infection by Brucella melitensis in bucks |
| title_sort | histopathology and immunohistochemistry assessments of acute experimental infection by brucella melitensis in bucks |
| url | http://psasir.upm.edu.my/id/eprint/37871/ http://psasir.upm.edu.my/id/eprint/37871/ http://psasir.upm.edu.my/id/eprint/37871/ http://psasir.upm.edu.my/id/eprint/37871/1/Histopathology%20and%20immunohistochemistry%20assessments%20of%20acute%20experimental%20infection%20by%20Brucella%20melitensis%20in%20bucks.pdf |