Anti-diabetic activity of red pitaya (Hylocereus polyrhizus) fruit
This study investigated the anti-insulin resistant activity of red pitaya (Hylocereus polyrhizus) fruit. Fresh pitaya along with two heat-processed pitaya samples with different proportions of phenolic contents, scavenging activities, and soluble dietary fibers were tested in insulin resistant rats...
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| Format: | Article |
| Language: | English |
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Royal Society of Chemistry
2014
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| Online Access: | http://psasir.upm.edu.my/id/eprint/36473/ http://psasir.upm.edu.my/id/eprint/36473/1/Anti-diabetic%20activity%20of%20red%20pitaya%20%28Hylocereus%20polyrhizus%29%20fruit.pdf |
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| author | Omidizadeh, Alireza Mohd Yusof, Rokiah Roohinejad, Shahin Ismail, Amin Abu Bakar @ Zakaria, Md Zuki Bekhit, Alaa El-Din A. |
| author_facet | Omidizadeh, Alireza Mohd Yusof, Rokiah Roohinejad, Shahin Ismail, Amin Abu Bakar @ Zakaria, Md Zuki Bekhit, Alaa El-Din A. |
| author_sort | Omidizadeh, Alireza |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | This study investigated the anti-insulin resistant activity of red pitaya (Hylocereus polyrhizus) fruit. Fresh pitaya along with two heat-processed pitaya samples with different proportions of phenolic contents, scavenging activities, and soluble dietary fibers were tested in insulin resistant rats over 6 weeks of treatment in a cause-effect study to investigate the anti-insulin resistant components of red pitaya. The results showed that fresh pitaya significantly (p < 0.05) attenuated the insulin resistance, hypertriglyceridemia and atherosclerotic changes induced by fructose supplement in rats. Thermally-treated pitaya at 95 °C for 30 min (containing a low antioxidant content) significantly (p < 0.05) improved hyperinsulinemia. Thermally-treated pitaya at 105 °C for 60 min (containing a low antioxidant and soluble dietary fiber content) fed to rats had no significant effect on insulin resistance, dyslipidemia and atherogenesis. Based on this study, the anti-insulin resistant effect of red pitaya can be attributed to its antioxidant and soluble dietary fiber contents. |
| first_indexed | 2025-11-15T09:32:58Z |
| format | Article |
| id | upm-36473 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T09:32:58Z |
| publishDate | 2014 |
| publisher | Royal Society of Chemistry |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-364732016-11-16T04:49:04Z http://psasir.upm.edu.my/id/eprint/36473/ Anti-diabetic activity of red pitaya (Hylocereus polyrhizus) fruit Omidizadeh, Alireza Mohd Yusof, Rokiah Roohinejad, Shahin Ismail, Amin Abu Bakar @ Zakaria, Md Zuki Bekhit, Alaa El-Din A. This study investigated the anti-insulin resistant activity of red pitaya (Hylocereus polyrhizus) fruit. Fresh pitaya along with two heat-processed pitaya samples with different proportions of phenolic contents, scavenging activities, and soluble dietary fibers were tested in insulin resistant rats over 6 weeks of treatment in a cause-effect study to investigate the anti-insulin resistant components of red pitaya. The results showed that fresh pitaya significantly (p < 0.05) attenuated the insulin resistance, hypertriglyceridemia and atherosclerotic changes induced by fructose supplement in rats. Thermally-treated pitaya at 95 °C for 30 min (containing a low antioxidant content) significantly (p < 0.05) improved hyperinsulinemia. Thermally-treated pitaya at 105 °C for 60 min (containing a low antioxidant and soluble dietary fiber content) fed to rats had no significant effect on insulin resistance, dyslipidemia and atherogenesis. Based on this study, the anti-insulin resistant effect of red pitaya can be attributed to its antioxidant and soluble dietary fiber contents. Royal Society of Chemistry 2014 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/36473/1/Anti-diabetic%20activity%20of%20red%20pitaya%20%28Hylocereus%20polyrhizus%29%20fruit.pdf Omidizadeh, Alireza and Mohd Yusof, Rokiah and Roohinejad, Shahin and Ismail, Amin and Abu Bakar @ Zakaria, Md Zuki and Bekhit, Alaa El-Din A. (2014) Anti-diabetic activity of red pitaya (Hylocereus polyrhizus) fruit. RSC Advances, 4 (108). pp. 62978-62986. ISSN 2046-2069 10.1039/C4RA10789F |
| spellingShingle | Omidizadeh, Alireza Mohd Yusof, Rokiah Roohinejad, Shahin Ismail, Amin Abu Bakar @ Zakaria, Md Zuki Bekhit, Alaa El-Din A. Anti-diabetic activity of red pitaya (Hylocereus polyrhizus) fruit |
| title | Anti-diabetic activity of red pitaya (Hylocereus polyrhizus) fruit |
| title_full | Anti-diabetic activity of red pitaya (Hylocereus polyrhizus) fruit |
| title_fullStr | Anti-diabetic activity of red pitaya (Hylocereus polyrhizus) fruit |
| title_full_unstemmed | Anti-diabetic activity of red pitaya (Hylocereus polyrhizus) fruit |
| title_short | Anti-diabetic activity of red pitaya (Hylocereus polyrhizus) fruit |
| title_sort | anti-diabetic activity of red pitaya (hylocereus polyrhizus) fruit |
| url | http://psasir.upm.edu.my/id/eprint/36473/ http://psasir.upm.edu.my/id/eprint/36473/ http://psasir.upm.edu.my/id/eprint/36473/1/Anti-diabetic%20activity%20of%20red%20pitaya%20%28Hylocereus%20polyrhizus%29%20fruit.pdf |