Antihypertensive prescribing pattern and blood pressure control among hypertensive patients over a ten year period in a primary care setting in Malaysia

Suboptimal control blood pressure (BP) leads to multiple complications. This study aims to examine BP control and the change in prescribing pattern of antihypertensive agents over a 10-year period. Data was obtained from the 10-year retrospective cohort of randomly selected adult patients registered...

Full description

Bibliographic Details
Main Authors: Chia, Yook Chin, Keevil, Victoria L., Ching, Siew Mooi
Format: Article
Language:English
Published: Marsland Press 2013
Online Access:http://psasir.upm.edu.my/id/eprint/29619/
http://psasir.upm.edu.my/id/eprint/29619/1/Antihypertensive%20prescribing%20pattern%20and%20blood%20pressure%20control%20among%20hypertensive%20patients%20over%20a%20ten%20year%20period%20in%20a%20primary%20care%20setting%20in%20Malaysia.pdf
_version_ 1848846449313316864
author Chia, Yook Chin
Keevil, Victoria L.
Ching, Siew Mooi
author_facet Chia, Yook Chin
Keevil, Victoria L.
Ching, Siew Mooi
author_sort Chia, Yook Chin
building UPM Institutional Repository
collection Online Access
description Suboptimal control blood pressure (BP) leads to multiple complications. This study aims to examine BP control and the change in prescribing pattern of antihypertensive agents over a 10-year period. Data was obtained from the 10-year retrospective cohort of randomly selected adult patients registered with the Department of Primary Care Medicine Clinic at the University of Malaya Medical Centre. Demographic data, BP and anti-hypertensive drug use in 1998, 2002 and 2007 were captured from patient records. Target BP control was defined as BP <140/90mmHg for those with hypertension alone and <130/80mmHg for those hypertensives with concomitant diabetes mellitus or chronic kidney disease. A total of 886 hypertensives patients were recruited. The mean age was 57.2 years (SD±9.6); 63.1% were female. The mean BP at baseline and at the end of 10-year were 146 / 87 (18/10) mmHg and 136/80 (16/9) mmHg respectively. In 1998, 74.3%, 22.5% and 1.6% were on monotherapy, 2 agents and ≥3 agents respectively. In 2007 after 10 years, 24.9%, 46.5% and 26.9% were on monotherapy, 2 agents and ≥3 agents respectively. At the end of 10 years there was improvement in overall blood pressure control, increasing from 15.6% in 1998 to 43.7% in 2007. However, the control rate of BP is still far from optimal in spite of an increase in the number of agents per patients used over a10 year follow-up. Based on our study the majority of patients with hypertension will need 2 or more agents to achieve target BP.
first_indexed 2025-11-15T09:02:53Z
format Article
id upm-29619
institution Universiti Putra Malaysia
institution_category Local University
language English
last_indexed 2025-11-15T09:02:53Z
publishDate 2013
publisher Marsland Press
recordtype eprints
repository_type Digital Repository
spelling upm-296192018-07-19T04:30:41Z http://psasir.upm.edu.my/id/eprint/29619/ Antihypertensive prescribing pattern and blood pressure control among hypertensive patients over a ten year period in a primary care setting in Malaysia Chia, Yook Chin Keevil, Victoria L. Ching, Siew Mooi Suboptimal control blood pressure (BP) leads to multiple complications. This study aims to examine BP control and the change in prescribing pattern of antihypertensive agents over a 10-year period. Data was obtained from the 10-year retrospective cohort of randomly selected adult patients registered with the Department of Primary Care Medicine Clinic at the University of Malaya Medical Centre. Demographic data, BP and anti-hypertensive drug use in 1998, 2002 and 2007 were captured from patient records. Target BP control was defined as BP <140/90mmHg for those with hypertension alone and <130/80mmHg for those hypertensives with concomitant diabetes mellitus or chronic kidney disease. A total of 886 hypertensives patients were recruited. The mean age was 57.2 years (SD±9.6); 63.1% were female. The mean BP at baseline and at the end of 10-year were 146 / 87 (18/10) mmHg and 136/80 (16/9) mmHg respectively. In 1998, 74.3%, 22.5% and 1.6% were on monotherapy, 2 agents and ≥3 agents respectively. In 2007 after 10 years, 24.9%, 46.5% and 26.9% were on monotherapy, 2 agents and ≥3 agents respectively. At the end of 10 years there was improvement in overall blood pressure control, increasing from 15.6% in 1998 to 43.7% in 2007. However, the control rate of BP is still far from optimal in spite of an increase in the number of agents per patients used over a10 year follow-up. Based on our study the majority of patients with hypertension will need 2 or more agents to achieve target BP. Marsland Press 2013 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/29619/1/Antihypertensive%20prescribing%20pattern%20and%20blood%20pressure%20control%20among%20hypertensive%20patients%20over%20a%20ten%20year%20period%20in%20a%20primary%20care%20setting%20in%20Malaysia.pdf Chia, Yook Chin and Keevil, Victoria L. and Ching, Siew Mooi (2013) Antihypertensive prescribing pattern and blood pressure control among hypertensive patients over a ten year period in a primary care setting in Malaysia. Life Science Journal, 10 (1). pp. 2031-2035. ISSN 1097-8135; ESSN: 2372-613X http://www.lifesciencesite.com/lsj/life1001/ 10.7537/marslsj100113.289
spellingShingle Chia, Yook Chin
Keevil, Victoria L.
Ching, Siew Mooi
Antihypertensive prescribing pattern and blood pressure control among hypertensive patients over a ten year period in a primary care setting in Malaysia
title Antihypertensive prescribing pattern and blood pressure control among hypertensive patients over a ten year period in a primary care setting in Malaysia
title_full Antihypertensive prescribing pattern and blood pressure control among hypertensive patients over a ten year period in a primary care setting in Malaysia
title_fullStr Antihypertensive prescribing pattern and blood pressure control among hypertensive patients over a ten year period in a primary care setting in Malaysia
title_full_unstemmed Antihypertensive prescribing pattern and blood pressure control among hypertensive patients over a ten year period in a primary care setting in Malaysia
title_short Antihypertensive prescribing pattern and blood pressure control among hypertensive patients over a ten year period in a primary care setting in Malaysia
title_sort antihypertensive prescribing pattern and blood pressure control among hypertensive patients over a ten year period in a primary care setting in malaysia
url http://psasir.upm.edu.my/id/eprint/29619/
http://psasir.upm.edu.my/id/eprint/29619/
http://psasir.upm.edu.my/id/eprint/29619/
http://psasir.upm.edu.my/id/eprint/29619/1/Antihypertensive%20prescribing%20pattern%20and%20blood%20pressure%20control%20among%20hypertensive%20patients%20over%20a%20ten%20year%20period%20in%20a%20primary%20care%20setting%20in%20Malaysia.pdf