Optimized Synthesis of Lipase-Catalyzed 3-O-(3',3'-Dimethylsuccinyl)-Betulinic Acid by Immobilised Novozyme 435

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Optimized Synthesis of Lipase-Catalyzed 3-O-(3',3'-Dimethylsuccinyl)-Betulinic Acid by Immobilised Novozyme 435

The derivative of betulinic acid, 3-O-(3',3'-dimethylsuccinyl)-betulinic acid (5) was successfully synthesized by the reaction of betulinic acid and 2,2-dimethylsuccinic anhydride, catalyzed by immobilized lipase from Candida antartica (Novozyme 435) in chloroform. The structure of the pro...

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Bibliographic Details
Main Author:	Gunong @ Mohd Shah, Siti Aminah
Format:	Thesis
Language:	English
Published:	2010
Subjects:	Lipase - Case studies Acids - Analysis Enzymes - Analysis
Online Access:	http://psasir.upm.edu.my/id/eprint/19583/ http://psasir.upm.edu.my/id/eprint/19583/1/FS_2010_33_F.pdf

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