Optimized Synthesis of Lipase-Catalyzed 3-O-(3',3'-Dimethylsuccinyl)-Betulinic Acid by Immobilised Novozyme 435
The derivative of betulinic acid, 3-O-(3',3'-dimethylsuccinyl)-betulinic acid (5) was successfully synthesized by the reaction of betulinic acid and 2,2-dimethylsuccinic anhydride, catalyzed by immobilized lipase from Candida antartica (Novozyme 435) in chloroform. The structure of the pro...
| Main Author: | |
|---|---|
| Format: | Thesis |
| Language: | English |
| Published: |
2010
|
| Subjects: | |
| Online Access: | http://psasir.upm.edu.my/id/eprint/19583/ http://psasir.upm.edu.my/id/eprint/19583/1/FS_2010_33_F.pdf |