Pellitorine, a potential anti-cancer lead compound against HL60 and MCT-7 cell lines and microbial transformation of piperine from Piper nigrum.
Pellitorine (1), which was isolated from the roots of Piper nigrum, showed strong cytotoxic activities against HL60 and MCT-7 cell lines. Microbial transformation of piperine (2) gave a new compound 5-[3,4-(methylenedioxy)phenyl]-pent-2-ene piperidine (3). Two other alkaloids were also found from Pi...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English English |
| Published: |
MDPI
2010
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| Online Access: | http://psasir.upm.edu.my/id/eprint/16064/ http://psasir.upm.edu.my/id/eprint/16064/1/Pellitorine.pdf |