Effects of Strobilanthes crispus tea aqueous extracts on glucose and lipid profile in normal and streptozotocin-induced hyperglycemic rats.
Strobilanthes crispus (Acanthaceae) has been used traditionally as antidiabetic, diuretic, antilytic, and laxative and has been proven scientifically to possess high antioxidant activity, anti-AIDS, and anticancer properties. It is commonly consumed in the form of herbal tea. The ethnopharmacologica...
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| Format: | Article |
| Language: | English English |
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Springer Verlag
2006
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| Online Access: | http://psasir.upm.edu.my/id/eprint/14416/ http://psasir.upm.edu.my/id/eprint/14416/1/Effects%20of%20Strobilanthes%20crispus%20tea%20aqueous%20extracts%20on%20glucose%20and%20lipid%20profile%20in%20normal%20and%20streptozotocin.pdf |
| _version_ | 1848842387645792256 |
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| author | Abu Bakar, Mohd Fadzelly Rahmat, Asmah Othman, Fauziah |
| author_facet | Abu Bakar, Mohd Fadzelly Rahmat, Asmah Othman, Fauziah |
| author_sort | Abu Bakar, Mohd Fadzelly |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Strobilanthes crispus (Acanthaceae) has been used traditionally as antidiabetic, diuretic, antilytic, and laxative and has been proven scientifically to possess high antioxidant activity, anti-AIDS, and anticancer properties. It is commonly consumed in the form of herbal tea. The ethnopharmacological value of this plant, such as the development of nutraceutical S. crispus herbal tea (fermented and unfermented) and assessment of their antihyperglycemic properties were investigated. The antidiabetic properties of S. crispus fermented and unfermented tea was carried out in normal and streptozotocin-induced hyperglycaemic rats for 21 days. Glucose and lipid profile (total cholesterol, triglyceride, HDL-cholesterol, LDL-cholesterol) were determined at day 0 (baseline), day 7, and day 21. The results showed that the hot water extract of both fermented and unfermented S. crispus tea reduced blood glucose in hyperglycaemic rats. S. crispus unfermented tea also reduced glucose level in normal rat. Both fermented and unfermented S. crispus tea also showed to improve lipid profile. Antioxidant and polyphenol content that present in the extracts might contribute to the antihyperglycemic and antilipidemic properties. Further study is needed to be carried out in pre-clinical and clinical environment to prove its efficacy in human. |
| first_indexed | 2025-11-15T07:58:20Z |
| format | Article |
| id | upm-14416 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English English |
| last_indexed | 2025-11-15T07:58:20Z |
| publishDate | 2006 |
| publisher | Springer Verlag |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-144162015-12-09T02:40:18Z http://psasir.upm.edu.my/id/eprint/14416/ Effects of Strobilanthes crispus tea aqueous extracts on glucose and lipid profile in normal and streptozotocin-induced hyperglycemic rats. Abu Bakar, Mohd Fadzelly Rahmat, Asmah Othman, Fauziah Strobilanthes crispus (Acanthaceae) has been used traditionally as antidiabetic, diuretic, antilytic, and laxative and has been proven scientifically to possess high antioxidant activity, anti-AIDS, and anticancer properties. It is commonly consumed in the form of herbal tea. The ethnopharmacological value of this plant, such as the development of nutraceutical S. crispus herbal tea (fermented and unfermented) and assessment of their antihyperglycemic properties were investigated. The antidiabetic properties of S. crispus fermented and unfermented tea was carried out in normal and streptozotocin-induced hyperglycaemic rats for 21 days. Glucose and lipid profile (total cholesterol, triglyceride, HDL-cholesterol, LDL-cholesterol) were determined at day 0 (baseline), day 7, and day 21. The results showed that the hot water extract of both fermented and unfermented S. crispus tea reduced blood glucose in hyperglycaemic rats. S. crispus unfermented tea also reduced glucose level in normal rat. Both fermented and unfermented S. crispus tea also showed to improve lipid profile. Antioxidant and polyphenol content that present in the extracts might contribute to the antihyperglycemic and antilipidemic properties. Further study is needed to be carried out in pre-clinical and clinical environment to prove its efficacy in human. Springer Verlag 2006-03 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/14416/1/Effects%20of%20Strobilanthes%20crispus%20tea%20aqueous%20extracts%20on%20glucose%20and%20lipid%20profile%20in%20normal%20and%20streptozotocin.pdf Abu Bakar, Mohd Fadzelly and Rahmat, Asmah and Othman, Fauziah (2006) Effects of Strobilanthes crispus tea aqueous extracts on glucose and lipid profile in normal and streptozotocin-induced hyperglycemic rats. Plant Foods for Human Nutrition, 61 (1). pp. 6-11. ISSN 0921-9668; ESSN: 1573-9104 10.1007/s11130-006-0002-z English |
| spellingShingle | Abu Bakar, Mohd Fadzelly Rahmat, Asmah Othman, Fauziah Effects of Strobilanthes crispus tea aqueous extracts on glucose and lipid profile in normal and streptozotocin-induced hyperglycemic rats. |
| title | Effects of Strobilanthes crispus tea aqueous extracts on glucose and lipid profile in normal and streptozotocin-induced hyperglycemic rats. |
| title_full | Effects of Strobilanthes crispus tea aqueous extracts on glucose and lipid profile in normal and streptozotocin-induced hyperglycemic rats. |
| title_fullStr | Effects of Strobilanthes crispus tea aqueous extracts on glucose and lipid profile in normal and streptozotocin-induced hyperglycemic rats. |
| title_full_unstemmed | Effects of Strobilanthes crispus tea aqueous extracts on glucose and lipid profile in normal and streptozotocin-induced hyperglycemic rats. |
| title_short | Effects of Strobilanthes crispus tea aqueous extracts on glucose and lipid profile in normal and streptozotocin-induced hyperglycemic rats. |
| title_sort | effects of strobilanthes crispus tea aqueous extracts on glucose and lipid profile in normal and streptozotocin-induced hyperglycemic rats. |
| url | http://psasir.upm.edu.my/id/eprint/14416/ http://psasir.upm.edu.my/id/eprint/14416/ http://psasir.upm.edu.my/id/eprint/14416/1/Effects%20of%20Strobilanthes%20crispus%20tea%20aqueous%20extracts%20on%20glucose%20and%20lipid%20profile%20in%20normal%20and%20streptozotocin.pdf |