Comparative analysis of microbial diversity in various kombucha starter cultures in Malaysia using the random amplified polymorphic DNA (RAPD) approach

Kombucha is sweetened black tea fermented with symbiotic culture of bacteria and yeasts (SCOBY) and has been widely consumed for its purported health benefits. The microbial consortium in kombucha is dominated by yeasts such as Brettanomyces sp. and Zygosaccharomyces sp., as well as acetic acid bact...

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Main Authors: Augustine, Nur Syafiqah Syahmimie, Chong, Eric Tzyy Jiann, Wong, Clemente Michael Vui Ling, Nasir, Nurul Farhana
Format: Article
Language:English
Published: University of Malaya 2025
Online Access:http://psasir.upm.edu.my/id/eprint/121044/
http://psasir.upm.edu.my/id/eprint/121044/1/121044.pdf
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author Augustine, Nur Syafiqah Syahmimie
Chong, Eric Tzyy Jiann
Wong, Clemente Michael Vui Ling
Nasir, Nurul Farhana
author_facet Augustine, Nur Syafiqah Syahmimie
Chong, Eric Tzyy Jiann
Wong, Clemente Michael Vui Ling
Nasir, Nurul Farhana
author_sort Augustine, Nur Syafiqah Syahmimie
building UPM Institutional Repository
collection Online Access
description Kombucha is sweetened black tea fermented with symbiotic culture of bacteria and yeasts (SCOBY) and has been widely consumed for its purported health benefits. The microbial consortium in kombucha is dominated by yeasts such as Brettanomyces sp. and Zygosaccharomyces sp., as well as acetic acid bacteria (AAB), Komagataeibacter sp. and Acetobacter sp. However, the source of SCOBY and substrates used may affect the microbial diversity as well as the biochemical, and flavour of the kombucha. Identifying the microbial population is important as the use of undefined starter cultures may lead to variable metabolite production and increase the risk of food pathogen contamination which can pose harm to human health. This study aims to isolate the microbes from kombucha in Malaysia for the future development of a new starter culture with specific species for the safe consumption of kombucha. Briefly, a total of 100 colonies were isolated from nine kombucha starter cultures with selective culture plates. Differences in colony morphology were observed based on their colours, surface texture, elevation, and margin. Their phenotypic morphology and genetic diversity were screened using microscopic examination, coupled with a catalase test and random amplified polymorphic DNA (RAPD), respectively. Based on the data, 51% of the isolates showed yeasts morphology under microscopic examination, while the rest were bacteria. Additionally, 55.79% of the isolates showed distinct banding profile patterns in the RAPD assessments. In conclusion, the data of this study shows that there is a diverse microbial consortium in different starter cultures of kombucha from Malaysia, mainly predominated by Gram-negative AAB and Gram-positive yeasts. Identification at the species level is to be conducted in the future. By understanding the microbiota diversity in kombucha, it contributes to the development and production of a safe functional drink.
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spelling upm-1210442025-10-23T02:11:15Z http://psasir.upm.edu.my/id/eprint/121044/ Comparative analysis of microbial diversity in various kombucha starter cultures in Malaysia using the random amplified polymorphic DNA (RAPD) approach Augustine, Nur Syafiqah Syahmimie Chong, Eric Tzyy Jiann Wong, Clemente Michael Vui Ling Nasir, Nurul Farhana Kombucha is sweetened black tea fermented with symbiotic culture of bacteria and yeasts (SCOBY) and has been widely consumed for its purported health benefits. The microbial consortium in kombucha is dominated by yeasts such as Brettanomyces sp. and Zygosaccharomyces sp., as well as acetic acid bacteria (AAB), Komagataeibacter sp. and Acetobacter sp. However, the source of SCOBY and substrates used may affect the microbial diversity as well as the biochemical, and flavour of the kombucha. Identifying the microbial population is important as the use of undefined starter cultures may lead to variable metabolite production and increase the risk of food pathogen contamination which can pose harm to human health. This study aims to isolate the microbes from kombucha in Malaysia for the future development of a new starter culture with specific species for the safe consumption of kombucha. Briefly, a total of 100 colonies were isolated from nine kombucha starter cultures with selective culture plates. Differences in colony morphology were observed based on their colours, surface texture, elevation, and margin. Their phenotypic morphology and genetic diversity were screened using microscopic examination, coupled with a catalase test and random amplified polymorphic DNA (RAPD), respectively. Based on the data, 51% of the isolates showed yeasts morphology under microscopic examination, while the rest were bacteria. Additionally, 55.79% of the isolates showed distinct banding profile patterns in the RAPD assessments. In conclusion, the data of this study shows that there is a diverse microbial consortium in different starter cultures of kombucha from Malaysia, mainly predominated by Gram-negative AAB and Gram-positive yeasts. Identification at the species level is to be conducted in the future. By understanding the microbiota diversity in kombucha, it contributes to the development and production of a safe functional drink. University of Malaya 2025 Article PeerReviewed text en cc_by_nc_4 http://psasir.upm.edu.my/id/eprint/121044/1/121044.pdf Augustine, Nur Syafiqah Syahmimie and Chong, Eric Tzyy Jiann and Wong, Clemente Michael Vui Ling and Nasir, Nurul Farhana (2025) Comparative analysis of microbial diversity in various kombucha starter cultures in Malaysia using the random amplified polymorphic DNA (RAPD) approach. Asia-Pacific Journal of Molecular Biology and Biotechnology, 33 (1). pp. 1-10. ISSN 0128-7451; eISSN: 2672-7277 https://www.msmbb.my/images/publication/volume_33/issue_1/01-Augustine-et-al.pdf 10.35118/apjmbb.2025.033.1.01
spellingShingle Augustine, Nur Syafiqah Syahmimie
Chong, Eric Tzyy Jiann
Wong, Clemente Michael Vui Ling
Nasir, Nurul Farhana
Comparative analysis of microbial diversity in various kombucha starter cultures in Malaysia using the random amplified polymorphic DNA (RAPD) approach
title Comparative analysis of microbial diversity in various kombucha starter cultures in Malaysia using the random amplified polymorphic DNA (RAPD) approach
title_full Comparative analysis of microbial diversity in various kombucha starter cultures in Malaysia using the random amplified polymorphic DNA (RAPD) approach
title_fullStr Comparative analysis of microbial diversity in various kombucha starter cultures in Malaysia using the random amplified polymorphic DNA (RAPD) approach
title_full_unstemmed Comparative analysis of microbial diversity in various kombucha starter cultures in Malaysia using the random amplified polymorphic DNA (RAPD) approach
title_short Comparative analysis of microbial diversity in various kombucha starter cultures in Malaysia using the random amplified polymorphic DNA (RAPD) approach
title_sort comparative analysis of microbial diversity in various kombucha starter cultures in malaysia using the random amplified polymorphic dna (rapd) approach
url http://psasir.upm.edu.my/id/eprint/121044/
http://psasir.upm.edu.my/id/eprint/121044/
http://psasir.upm.edu.my/id/eprint/121044/
http://psasir.upm.edu.my/id/eprint/121044/1/121044.pdf