Safety profile of sikamat virus and its oncolytic potential in leukemic cells and cancer stem cells

Leukaemia remains a global health concern. The oncotherapy resistance of leukaemia might be due to the existence of cancer stem cell populations. This study investigated the therapeutic potential of Sikamat virus (PRV7S), a Pteropine orthoreovirus, as an oncolytic virus against acute myeloid leukaem...

Full description

Bibliographic Details
Main Authors: Siew, Zhen Yun, Ong, Ghee Khang, Wong, Siew Tung, Leong, Pooi Pooi, Tan, Boon Shing, Leong, Chee-Onn, Chupri, Juita, Fang, Chee-Mun, Voon, Kenny
Format: Article
Language:English
Published: Nature Research 2025
Online Access:http://psasir.upm.edu.my/id/eprint/120642/
http://psasir.upm.edu.my/id/eprint/120642/1/120642.pdf