Dysregulation of REST and its target genes impacts the fate of neural progenitor cells in down syndrome

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Dysregulation of REST and its target genes impacts the fate of neural progenitor cells in down syndrome

Increasing shreds of evidence suggest that neurogenic-to-gliogenic shift may be critical to the abnormal neurodevelopment observed in individuals with Down syndrome (DS). REST, the Repressor Element-1 Silencing Transcription factor, regulates the differentiation and development of neural cells. Down...

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Bibliographic Details
Main Authors:	Tan, Huang, Fakurazi, Sharida, Cheah, Pike-See, Ling, King-Hwa
Format:	Article
Language:	English
Published:	Nature Research 2025
Online Access:	http://psasir.upm.edu.my/id/eprint/120219/ http://psasir.upm.edu.my/id/eprint/120219/1/120219.pdf

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