Dysregulation of REST and its target genes impacts the fate of neural progenitor cells in down syndrome
Increasing shreds of evidence suggest that neurogenic-to-gliogenic shift may be critical to the abnormal neurodevelopment observed in individuals with Down syndrome (DS). REST, the Repressor Element-1 Silencing Transcription factor, regulates the differentiation and development of neural cells. Down...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Research
2025
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| Online Access: | http://psasir.upm.edu.my/id/eprint/120219/ http://psasir.upm.edu.my/id/eprint/120219/1/120219.pdf |