Antileishmanial, insecticidal, anti-leukemic, phytotoxicity and anti-pancreatic lipase effects of ethanolic extracts of Moringa peregrina Seed
In this study, the ethanolic extracts of Moringa peregrina seeds (MPSE) were evaluated for their antiparasitic, insecticidal, herbicidal, anti-leukemic, and anti-pancreatic lipase activities. The MPSE showed moderate antileishmanial activity against Leishmania major with an IC50 of 71.7 ± 0.46 μg/mL...
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| Format: | Article |
| Language: | English |
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MS Editions
2025
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| Online Access: | http://psasir.upm.edu.my/id/eprint/117592/ http://psasir.upm.edu.my/id/eprint/117592/1/117592.pdf |
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| author | Albaayit, Shaymaa Fadhel Abbas Maharjan, Rukesh Abdullah, Rasedee Mohd Noor, Mohd Hezmee Ullah, Saeed Al-Azzawi, Sura Al-Khazraji, Husham Hussein Jasim |
| author_facet | Albaayit, Shaymaa Fadhel Abbas Maharjan, Rukesh Abdullah, Rasedee Mohd Noor, Mohd Hezmee Ullah, Saeed Al-Azzawi, Sura Al-Khazraji, Husham Hussein Jasim |
| author_sort | Albaayit, Shaymaa Fadhel Abbas |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | In this study, the ethanolic extracts of Moringa peregrina seeds (MPSE) were evaluated for their antiparasitic, insecticidal, herbicidal, anti-leukemic, and anti-pancreatic lipase activities. The MPSE showed moderate antileishmanial activity against Leishmania major with an IC50 of 71.7 ± 0.46 μg/mL, compared to 10 ± 0.05 μg/mL and 4 ± 0.05 μg/mL for pentamidine and amphotericin B, respectively. The extract demonstrated moderate insecticidal activity with 41% mortality in Rhyzopertha dominica and 15.7% in Tribolium castaneum. MPSE exhibited potent herbicidal activity against Lemna minor at 1000 µg/mL. Additionally, MPSE inhibited the proliferation of leukemia K562 cells with an IC50 of 25 μg/mL and porcine pancreatic lipase with an IC50 of 83.7 ± 0.57 μg/mL. These findings suggest that MPSE may be beneficial as an antiparasitic, insecticidal, herbicidal, anti-leukemic, and anti-pancreatic lipase agent. |
| first_indexed | 2025-11-15T14:34:09Z |
| format | Article |
| id | upm-117592 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T14:34:09Z |
| publishDate | 2025 |
| publisher | MS Editions |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-1175922025-05-30T02:55:42Z http://psasir.upm.edu.my/id/eprint/117592/ Antileishmanial, insecticidal, anti-leukemic, phytotoxicity and anti-pancreatic lipase effects of ethanolic extracts of Moringa peregrina Seed Albaayit, Shaymaa Fadhel Abbas Maharjan, Rukesh Abdullah, Rasedee Mohd Noor, Mohd Hezmee Ullah, Saeed Al-Azzawi, Sura Al-Khazraji, Husham Hussein Jasim In this study, the ethanolic extracts of Moringa peregrina seeds (MPSE) were evaluated for their antiparasitic, insecticidal, herbicidal, anti-leukemic, and anti-pancreatic lipase activities. The MPSE showed moderate antileishmanial activity against Leishmania major with an IC50 of 71.7 ± 0.46 μg/mL, compared to 10 ± 0.05 μg/mL and 4 ± 0.05 μg/mL for pentamidine and amphotericin B, respectively. The extract demonstrated moderate insecticidal activity with 41% mortality in Rhyzopertha dominica and 15.7% in Tribolium castaneum. MPSE exhibited potent herbicidal activity against Lemna minor at 1000 µg/mL. Additionally, MPSE inhibited the proliferation of leukemia K562 cells with an IC50 of 25 μg/mL and porcine pancreatic lipase with an IC50 of 83.7 ± 0.57 μg/mL. These findings suggest that MPSE may be beneficial as an antiparasitic, insecticidal, herbicidal, anti-leukemic, and anti-pancreatic lipase agent. MS Editions 2025 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/117592/1/117592.pdf Albaayit, Shaymaa Fadhel Abbas and Maharjan, Rukesh and Abdullah, Rasedee and Mohd Noor, Mohd Hezmee and Ullah, Saeed and Al-Azzawi, Sura and Al-Khazraji, Husham Hussein Jasim (2025) Antileishmanial, insecticidal, anti-leukemic, phytotoxicity and anti-pancreatic lipase effects of ethanolic extracts of Moringa peregrina Seed. Boletin Latinoamericano Y Del Caribe De Plantas Medicinales Y Aromáticas, 24 (2). pp. 225-235. ISSN 0717-7917 https://www.blacpma.ms-editions.cl/index.php/blacpma/article/view/482/513 10.37360/blacpma.25.24.2.16 |
| spellingShingle | Albaayit, Shaymaa Fadhel Abbas Maharjan, Rukesh Abdullah, Rasedee Mohd Noor, Mohd Hezmee Ullah, Saeed Al-Azzawi, Sura Al-Khazraji, Husham Hussein Jasim Antileishmanial, insecticidal, anti-leukemic, phytotoxicity and anti-pancreatic lipase effects of ethanolic extracts of Moringa peregrina Seed |
| title | Antileishmanial, insecticidal, anti-leukemic, phytotoxicity and anti-pancreatic lipase effects of ethanolic extracts of Moringa peregrina Seed |
| title_full | Antileishmanial, insecticidal, anti-leukemic, phytotoxicity and anti-pancreatic lipase effects of ethanolic extracts of Moringa peregrina Seed |
| title_fullStr | Antileishmanial, insecticidal, anti-leukemic, phytotoxicity and anti-pancreatic lipase effects of ethanolic extracts of Moringa peregrina Seed |
| title_full_unstemmed | Antileishmanial, insecticidal, anti-leukemic, phytotoxicity and anti-pancreatic lipase effects of ethanolic extracts of Moringa peregrina Seed |
| title_short | Antileishmanial, insecticidal, anti-leukemic, phytotoxicity and anti-pancreatic lipase effects of ethanolic extracts of Moringa peregrina Seed |
| title_sort | antileishmanial, insecticidal, anti-leukemic, phytotoxicity and anti-pancreatic lipase effects of ethanolic extracts of moringa peregrina seed |
| url | http://psasir.upm.edu.my/id/eprint/117592/ http://psasir.upm.edu.my/id/eprint/117592/ http://psasir.upm.edu.my/id/eprint/117592/ http://psasir.upm.edu.my/id/eprint/117592/1/117592.pdf |