Reduced REST expression in neural progenitor cells, adult cortex, and impaired REST nuclear translocation in the prefrontal cortex of Ts1Cje mouse model of Down Syndrome

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Reduced REST expression in neural progenitor cells, adult cortex, and impaired REST nuclear translocation in the prefrontal cortex of Ts1Cje mouse model of Down Syndrome

Abstract—Down syndrome (DS) is a common genetic disorder caused by trisomy of human chromosome 21. DS individuals have neurodevelopmental defects that lead to the manifestation of neurological and neuropsychiatric disorders. Repressor element-1 silencing transcription factor (REST) is the key epigen...

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Bibliographic Details
Main Authors:	Chong, Teik Lim, Lam, Xin Jieh, Crystal, Arthini Arrumugam, Huang, Tan, Jusoh, Norhazlin, Cheah, Pike See, Ling, King Hwa
Format:	Article
Language:	English
Published:	Pleiades Publishing 2024
Online Access:	http://psasir.upm.edu.my/id/eprint/117088/ http://psasir.upm.edu.my/id/eprint/117088/1/117088.pdf

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