Reduced REST expression in neural progenitor cells, adult cortex, and impaired REST nuclear translocation in the prefrontal cortex of Ts1Cje mouse model of Down Syndrome

Reduced REST expression in neural progenitor cells, adult cortex, and impaired REST nuclear translocation in the prefrontal cortex of Ts1Cje mouse model of Down Syndrome

Abstract—Down syndrome (DS) is a common genetic disorder caused by trisomy of human chromosome 21. DS individuals have neurodevelopmental defects that lead to the manifestation of neurological and neuropsychiatric disorders. Repressor element-1 silencing transcription factor (REST) is the key epigen...

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Bibliographic Details
Main Authors: Chong, Teik Lim, Lam, Xin Jieh, Crystal, Arthini Arrumugam, Huang, Tan, Jusoh, Norhazlin, Cheah, Pike See, Ling, King Hwa
Format: Article
Language:English
Published: Pleiades Publishing 2024
Online Access:http://psasir.upm.edu.my/id/eprint/117088/
http://psasir.upm.edu.my/id/eprint/117088/1/117088.pdf

Internet

http://psasir.upm.edu.my/id/eprint/117088/
http://psasir.upm.edu.my/id/eprint/117088/1/117088.pdf

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