Effect of roselle (Hibiscus sabdariffa L.) on serum lipids of Sprague Dawley rats
The efficacy of roselle as a functional food has been revealed lately, especially for its antioxidant bioactivity. In this study, the benefits of roselle were further studied in vivo using the model of male Sprague Dawley rats fed with normal diets (C), 2.5 percent roselle (R), 2.5 percent roselle w...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
2002
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| Online Access: | http://psasir.upm.edu.my/id/eprint/116371/ http://psasir.upm.edu.my/id/eprint/116371/1/116371.pdf |
| _version_ | 1848866988087050240 |
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| author | Tee, Pau‐Ling Yusof, Salmah Mohamed, Suhaila Umar, Nor Aimi Mohamed Mustapha, Noordin |
| author_facet | Tee, Pau‐Ling Yusof, Salmah Mohamed, Suhaila Umar, Nor Aimi Mohamed Mustapha, Noordin |
| author_sort | Tee, Pau‐Ling |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | The efficacy of roselle as a functional food has been revealed lately, especially for its antioxidant bioactivity. In this study, the benefits of roselle were further studied in vivo using the model of male Sprague Dawley rats fed with normal diets (C), 2.5 percent roselle (R), 2.5 percent roselle with 15 percent soybean oil (RO) and 15 percent soybean oil (O) for 25 weeks. The results demonstrated that supplementation of roselle in the diets significantly (p < 0.05) reduced the gross body weight and increased the highdensity lipoproteins cholesterol (HDLC) compared to the rats fed with normal diets and oil diets, and reduced the level of triglycerides in the serum. Serum total cholesterol of R group decreased compared to C but increased in RO compared to O group. Significant increase (p < 0.05) of serum uric acid was observed in R group at week 15 and 20. Addition of roselle in oil diet significantly decreased (p < 0.05) the malondialdehyde formation at week 20 and 25 but there was no significant effect of roselle on the catalase activity among the treatments at all time points. Suggests that roselle might play a role in the prevention of atherosclerosis and obesity. © 2002, MCB UP Limited |
| first_indexed | 2025-11-15T14:29:20Z |
| format | Article |
| id | upm-116371 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T14:29:20Z |
| publishDate | 2002 |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-1163712025-03-27T05:08:13Z http://psasir.upm.edu.my/id/eprint/116371/ Effect of roselle (Hibiscus sabdariffa L.) on serum lipids of Sprague Dawley rats Tee, Pau‐Ling Yusof, Salmah Mohamed, Suhaila Umar, Nor Aimi Mohamed Mustapha, Noordin The efficacy of roselle as a functional food has been revealed lately, especially for its antioxidant bioactivity. In this study, the benefits of roselle were further studied in vivo using the model of male Sprague Dawley rats fed with normal diets (C), 2.5 percent roselle (R), 2.5 percent roselle with 15 percent soybean oil (RO) and 15 percent soybean oil (O) for 25 weeks. The results demonstrated that supplementation of roselle in the diets significantly (p < 0.05) reduced the gross body weight and increased the highdensity lipoproteins cholesterol (HDLC) compared to the rats fed with normal diets and oil diets, and reduced the level of triglycerides in the serum. Serum total cholesterol of R group decreased compared to C but increased in RO compared to O group. Significant increase (p < 0.05) of serum uric acid was observed in R group at week 15 and 20. Addition of roselle in oil diet significantly decreased (p < 0.05) the malondialdehyde formation at week 20 and 25 but there was no significant effect of roselle on the catalase activity among the treatments at all time points. Suggests that roselle might play a role in the prevention of atherosclerosis and obesity. © 2002, MCB UP Limited 2002 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/116371/1/116371.pdf Tee, Pau‐Ling and Yusof, Salmah and Mohamed, Suhaila and Umar, Nor Aimi and Mohamed Mustapha, Noordin (2002) Effect of roselle (Hibiscus sabdariffa L.) on serum lipids of Sprague Dawley rats. Nutrition & Food Science, 32 (5). pp. 190-196. ISSN 0034-6659; eISSN: 0034-6659 https://www.emerald.com/insight/content/doi/10.1108/00346650210445758/full/html 10.1108/00346650210445758 |
| spellingShingle | Tee, Pau‐Ling Yusof, Salmah Mohamed, Suhaila Umar, Nor Aimi Mohamed Mustapha, Noordin Effect of roselle (Hibiscus sabdariffa L.) on serum lipids of Sprague Dawley rats |
| title | Effect of roselle (Hibiscus sabdariffa L.) on serum lipids of Sprague Dawley rats |
| title_full | Effect of roselle (Hibiscus sabdariffa L.) on serum lipids of Sprague Dawley rats |
| title_fullStr | Effect of roselle (Hibiscus sabdariffa L.) on serum lipids of Sprague Dawley rats |
| title_full_unstemmed | Effect of roselle (Hibiscus sabdariffa L.) on serum lipids of Sprague Dawley rats |
| title_short | Effect of roselle (Hibiscus sabdariffa L.) on serum lipids of Sprague Dawley rats |
| title_sort | effect of roselle (hibiscus sabdariffa l.) on serum lipids of sprague dawley rats |
| url | http://psasir.upm.edu.my/id/eprint/116371/ http://psasir.upm.edu.my/id/eprint/116371/ http://psasir.upm.edu.my/id/eprint/116371/ http://psasir.upm.edu.my/id/eprint/116371/1/116371.pdf |