Cassia alata and its phytochemicals: a promising natural strategy in wound recovery
Cassia alata, a traditional herb with a global presence, is renowned for its anti‑inflammatory, antibacterial, and antifungal properties, making it a go‑to remedy for skin ailments. While it has demonstrated wound healing capabilities in both in vitro and in vivo studies, the precise mechanisms rema...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Multidisciplinary Digital Publishing Institute (MDPI)
2024
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| Online Access: | http://psasir.upm.edu.my/id/eprint/116279/ http://psasir.upm.edu.my/id/eprint/116279/1/116279.pdf |
| _version_ | 1848866966471704576 |
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| author | Keng, Jing Wen Lee, Sue Kei Sang, Sze Huey Liew, Kai Bin Teo, Swee Sen Shaik Mohamed Mossadeq, Wan Mastura Chow, Sek Chuen Akowuah, Gabriel Akyirem Lee, Siew Keah Mai, Chun Wai Chew, Yik Ling |
| author_facet | Keng, Jing Wen Lee, Sue Kei Sang, Sze Huey Liew, Kai Bin Teo, Swee Sen Shaik Mohamed Mossadeq, Wan Mastura Chow, Sek Chuen Akowuah, Gabriel Akyirem Lee, Siew Keah Mai, Chun Wai Chew, Yik Ling |
| author_sort | Keng, Jing Wen |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Cassia alata, a traditional herb with a global presence, is renowned for its anti‑inflammatory, antibacterial, and antifungal properties, making it a go‑to remedy for skin ailments. While it has demonstrated wound healing capabilities in both in vitro and in vivo studies, the precise mechanisms remain elusive. This review aims to highlight its key phytochemicals, their effects, and the mechanism of action. The compounds that have been reviewed and discussed include kaempferol, apigenin, quercetin, rhein, and rutin. These polyphenols play important roles in normal and impaired wound healing processes, encompassing hemostasis, inflammation, proliferation, and tissue remodeling. |
| first_indexed | 2025-11-15T14:29:00Z |
| format | Article |
| id | upm-116279 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T14:29:00Z |
| publishDate | 2024 |
| publisher | Multidisciplinary Digital Publishing Institute (MDPI) |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-1162792025-03-24T06:52:56Z http://psasir.upm.edu.my/id/eprint/116279/ Cassia alata and its phytochemicals: a promising natural strategy in wound recovery Keng, Jing Wen Lee, Sue Kei Sang, Sze Huey Liew, Kai Bin Teo, Swee Sen Shaik Mohamed Mossadeq, Wan Mastura Chow, Sek Chuen Akowuah, Gabriel Akyirem Lee, Siew Keah Mai, Chun Wai Chew, Yik Ling Cassia alata, a traditional herb with a global presence, is renowned for its anti‑inflammatory, antibacterial, and antifungal properties, making it a go‑to remedy for skin ailments. While it has demonstrated wound healing capabilities in both in vitro and in vivo studies, the precise mechanisms remain elusive. This review aims to highlight its key phytochemicals, their effects, and the mechanism of action. The compounds that have been reviewed and discussed include kaempferol, apigenin, quercetin, rhein, and rutin. These polyphenols play important roles in normal and impaired wound healing processes, encompassing hemostasis, inflammation, proliferation, and tissue remodeling. Multidisciplinary Digital Publishing Institute (MDPI) 2024-06-03 Article PeerReviewed text en cc_by_4 http://psasir.upm.edu.my/id/eprint/116279/1/116279.pdf Keng, Jing Wen and Lee, Sue Kei and Sang, Sze Huey and Liew, Kai Bin and Teo, Swee Sen and Shaik Mohamed Mossadeq, Wan Mastura and Chow, Sek Chuen and Akowuah, Gabriel Akyirem and Lee, Siew Keah and Mai, Chun Wai and Chew, Yik Ling (2024) Cassia alata and its phytochemicals: a promising natural strategy in wound recovery. Sci, 6 (2). art. no. 34. pp. 1-23. ISSN 2413-4155 https://www.mdpi.com/2413-4155/6/2/34 10.3390/sci6020034 |
| spellingShingle | Keng, Jing Wen Lee, Sue Kei Sang, Sze Huey Liew, Kai Bin Teo, Swee Sen Shaik Mohamed Mossadeq, Wan Mastura Chow, Sek Chuen Akowuah, Gabriel Akyirem Lee, Siew Keah Mai, Chun Wai Chew, Yik Ling Cassia alata and its phytochemicals: a promising natural strategy in wound recovery |
| title | Cassia alata and its phytochemicals: a promising natural strategy in wound recovery |
| title_full | Cassia alata and its phytochemicals: a promising natural strategy in wound recovery |
| title_fullStr | Cassia alata and its phytochemicals: a promising natural strategy in wound recovery |
| title_full_unstemmed | Cassia alata and its phytochemicals: a promising natural strategy in wound recovery |
| title_short | Cassia alata and its phytochemicals: a promising natural strategy in wound recovery |
| title_sort | cassia alata and its phytochemicals: a promising natural strategy in wound recovery |
| url | http://psasir.upm.edu.my/id/eprint/116279/ http://psasir.upm.edu.my/id/eprint/116279/ http://psasir.upm.edu.my/id/eprint/116279/ http://psasir.upm.edu.my/id/eprint/116279/1/116279.pdf |