A cellular model for aromatic L-amino acid decarboxylase deficiency and neurotransmitter analysis of available therapeutics using a neuroblastoma cell culture

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A cellular model for aromatic L-amino acid decarboxylase deficiency and neurotransmitter analysis of available therapeutics using a neuroblastoma cell culture

Aromatic L-amino acid decarboxylase (AADC) deficiency is a rare pediatric neurotransmitter disease. It is an autosomal recessive genetic disorder affecting to date, less than 100 children worldwide. AADC is the key enzyme required for the synthesis of neurotransmitters in the catecholaminergic and s...

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Bibliographic Details
Main Author:	Khalid, Melati
Format:	Thesis
Language:	English
Published:	2015
Subjects:	Aromatic-L-Amino-Acid Decarboxylases - deficiency Genetic disorders in children
Online Access:	http://psasir.upm.edu.my/id/eprint/116025/ http://psasir.upm.edu.my/id/eprint/116025/1/116025.pdf

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