A cellular model for aromatic L-amino acid decarboxylase deficiency and neurotransmitter analysis of available therapeutics using a neuroblastoma cell culture
Aromatic L-amino acid decarboxylase (AADC) deficiency is a rare pediatric neurotransmitter disease. It is an autosomal recessive genetic disorder affecting to date, less than 100 children worldwide. AADC is the key enzyme required for the synthesis of neurotransmitters in the catecholaminergic and s...
| Main Author: | |
|---|---|
| Format: | Thesis |
| Language: | English |
| Published: |
2015
|
| Subjects: | |
| Online Access: | http://psasir.upm.edu.my/id/eprint/116025/ http://psasir.upm.edu.my/id/eprint/116025/1/116025.pdf |