Optimization of medium formulations for biomass vaccine production of gdhA derivative Pasteurella multocida B:2 using statistical experimental design
The glutamate dehydrogenase (gdhA) gene of a pathogenic Pasteurella multocida B:2 was successfully inactivated to create an attenuated strain as a vaccine candidate against hemorrhagic septicemia (HS) in ruminants. This study presents a novel approach to optimizing the medium formulation for high-th...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025
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| Online Access: | http://psasir.upm.edu.my/id/eprint/115934/ http://psasir.upm.edu.my/id/eprint/115934/1/115934.pdf |