Resistance of Pseudomonas pseudomallei to normal human serum bactericidal action
The effect of human normal serum (HNS) on Pseudomonas pseudomallei was determined. It is apparent from our data that the organism is resistant to the normal serum bactericidal mechanism. Ancillary experiments to confirm this serum-resistant property of P. pseudomallei were done by examining the effe...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
1988
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| Online Access: | http://psasir.upm.edu.my/id/eprint/115697/ http://psasir.upm.edu.my/id/eprint/115697/1/115697.pdf |
| _version_ | 1848866843610054656 |
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| author | Ismail, Ghazally Razak, Nyonya Mohamed, Rahmah Omar, Othman Embi, Noor |
| author_facet | Ismail, Ghazally Razak, Nyonya Mohamed, Rahmah Omar, Othman Embi, Noor |
| author_sort | Ismail, Ghazally |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | The effect of human normal serum (HNS) on Pseudomonas pseudomallei was determined. It is apparent from our data that the organism is resistant to the normal serum bactericidal mechanism. Ancillary experiments to confirm this serum-resistant property of P. pseudomallei were done by examining the effects of growth phase conditions of the bacteria (i.e., logarithmic and stationary phases) and different buffered systems used as diluent in our bactericidal assay. Results obtained showed similar degree of resistance to serum bactericidal killing by 5 strains of the organisms tested. The possible survival advantage of serum-resistant property to P. pseudomallei as bacterial pathogens known to invade the blood stream is discussed. |
| first_indexed | 2025-11-15T14:27:03Z |
| format | Article |
| id | upm-115697 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T14:27:03Z |
| publishDate | 1988 |
| publisher | Wiley |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-1156972025-03-10T07:51:11Z http://psasir.upm.edu.my/id/eprint/115697/ Resistance of Pseudomonas pseudomallei to normal human serum bactericidal action Ismail, Ghazally Razak, Nyonya Mohamed, Rahmah Omar, Othman Embi, Noor The effect of human normal serum (HNS) on Pseudomonas pseudomallei was determined. It is apparent from our data that the organism is resistant to the normal serum bactericidal mechanism. Ancillary experiments to confirm this serum-resistant property of P. pseudomallei were done by examining the effects of growth phase conditions of the bacteria (i.e., logarithmic and stationary phases) and different buffered systems used as diluent in our bactericidal assay. Results obtained showed similar degree of resistance to serum bactericidal killing by 5 strains of the organisms tested. The possible survival advantage of serum-resistant property to P. pseudomallei as bacterial pathogens known to invade the blood stream is discussed. Wiley 1988 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/115697/1/115697.pdf Ismail, Ghazally and Razak, Nyonya and Mohamed, Rahmah and Omar, Othman and Embi, Noor (1988) Resistance of Pseudomonas pseudomallei to normal human serum bactericidal action. Microbiology and Immunology, 32 (7). pp. 645-652. ISSN 0385-5600; eISSN: 1348-0421 https://onlinelibrary.wiley.com/doi/10.1111/j.1348-0421.1988.tb01426.x 10.1111/j.1348-0421.1988.tb01426.x |
| spellingShingle | Ismail, Ghazally Razak, Nyonya Mohamed, Rahmah Omar, Othman Embi, Noor Resistance of Pseudomonas pseudomallei to normal human serum bactericidal action |
| title | Resistance of Pseudomonas pseudomallei to normal human serum bactericidal action |
| title_full | Resistance of Pseudomonas pseudomallei to normal human serum bactericidal action |
| title_fullStr | Resistance of Pseudomonas pseudomallei to normal human serum bactericidal action |
| title_full_unstemmed | Resistance of Pseudomonas pseudomallei to normal human serum bactericidal action |
| title_short | Resistance of Pseudomonas pseudomallei to normal human serum bactericidal action |
| title_sort | resistance of pseudomonas pseudomallei to normal human serum bactericidal action |
| url | http://psasir.upm.edu.my/id/eprint/115697/ http://psasir.upm.edu.my/id/eprint/115697/ http://psasir.upm.edu.my/id/eprint/115697/ http://psasir.upm.edu.my/id/eprint/115697/1/115697.pdf |