Antitumor polycyclic acridines. 7. Synthesis and biological properties of DNA affinic tetra- and pentacyclic acridines
New synthetic routes to a series of tetra- and pentacyclic acridines related in structure to marine natural products are reported. The novel water-soluble agent dihydroindolizino[7,6,5-kl]acridinium chloride 14 has inhibitory activity in a panel of non-small-cell lung and breast tumor cell lines exc...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Published: |
American Chemical Society
2000
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| Online Access: | http://psasir.upm.edu.my/id/eprint/114416/ |