The role of TGFβ in human cancers
Transforming growth factor β (TGFβ) is secreted as a large latent precursor from both normal and transformed cells which needs to be activated for biological activity. The active TGFβ binds either directly to TβR-II or indirectly by binding to β-glycan which then presents the TGFβ to TβR-II. Formati...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2001
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| Online Access: | http://psasir.upm.edu.my/id/eprint/112551/ http://psasir.upm.edu.my/id/eprint/112551/3/112551.pdf |