Mitochondrial dysfunction in Down Syndrome: from pathology to therapy
Mitochondrial dysfunctions have been described in Down syndrome (DS) caused by either partial or full trisomy of chromosome 21 (HSA21). Mitochondria play a crucial role in various vital functions in eukaryotic cells, especially in energy production, calcium homeostasis and programmed cell death. The...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2023
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| Online Access: | http://psasir.upm.edu.my/id/eprint/109511/ http://psasir.upm.edu.my/id/eprint/109511/1/1-s2.0-S0306452222006030-main.pdf |