Increased efficacy of biologics following inhibition of autophagy in A549 lung cancer cells in bimodal treatment of doxorubicin and SAR405-loaded chitosan nanoparticles
Conventional anti-cancer drugs, including doxorubicin, are associated with high toxicity and non-specific distribution in the body which results in a cascade of side effects. Cancer cells can utilize autophagy to promote tolerance to the stress induced by anti-cancer agents; this may be the major ca...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Published: |
Elsevier
2023
|
| Online Access: | http://psasir.upm.edu.my/id/eprint/109118/ |