Effect of secretion efficiency of mutant KRAS neoantigen by Lactococcus lactis on the immune response of a mucosal vaccine delivery vehicle targeting colorectal cancer

Effect of secretion efficiency of mutant KRAS neoantigen by Lactococcus lactis on the immune response of a mucosal vaccine delivery vehicle targeting colorectal cancer

Colorectal cancer (CRC) is often caused by mutations in the KRAS oncogene, making KRAS neoantigens a promising vaccine candidate for immunotherapy. Secreting KRAS antigens using live Generally Recognized as Safe (GRAS) vaccine delivery hosts such as Lactococcus lactis is deemed to be an effective st...

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Bibliographic Details
Main Authors: Alias, Nur Aqlili Riana, Hoo, Winfrey Pui Yee, Siak, Pui Yan, Othman, Siti Sarah, Mohammed Alitheen, Noorjahan Banu, In, Lionel Lian Aun, Abdul Rahim, Raha, Song, Adelene Ai-Lian
Format: Article
Language:English
Published: Multidisciplinary Digital Publishing Institute 2023
Online Access:http://psasir.upm.edu.my/id/eprint/107528/
http://psasir.upm.edu.my/id/eprint/107528/1/Effect%20of%20secretion%20efficiency%20of%20mutant%20KRAS%20neoantigen%20by%20Lactococcus%20lactis.pdf

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http://psasir.upm.edu.my/id/eprint/107528/
http://psasir.upm.edu.my/id/eprint/107528/1/Effect%20of%20secretion%20efficiency%20of%20mutant%20KRAS%20neoantigen%20by%20Lactococcus%20lactis.pdf

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