Substituted benzo[i]phenanthridines as mammalian topoisomerase-Targeting agents

Substituted benzo[i]phenanthridines as mammalian topoisomerase-Targeting agents

Several benzo[c]phenanthridine and protoberberine alkaloids, such as nitidine and berberrubine, are known to induce DNA cleavage in the presence of either topoisomerase I or II. Structure–activity studies performed on various analogues related to benzo[c]phenanthridine and protoberberine alkaloids h...

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Bibliographic Details
Main Authors: Makhey, D., Li, D., Zhao, B., Sim, S.P, Li, TK, Liu, A., Liu, L.F., LaVoie, E.J.
Format: Article
Language:English
Published: Elsevier Ltd 2003
Subjects:
QD Chemistry
R Medicine (General)
Online Access:http://ir.unimas.my/id/eprint/2485/
http://ir.unimas.my/id/eprint/2485/1/Substituted%20benzo%5Bi%5Dphenanthridines%20as%20mammalian%20topoisomerase-Targeting%20agents.pdf

Internet

http://ir.unimas.my/id/eprint/2485/
http://ir.unimas.my/id/eprint/2485/1/Substituted%20benzo%5Bi%5Dphenanthridines%20as%20mammalian%20topoisomerase-Targeting%20agents.pdf

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