Oxidant Production, oxLDL uptake and CD36 levels in Human Monocyte Derived Macrophages are down regulated by the macrophage - generated antioxidant 7,8-dihydroneopterin
The severity of atheroma burden in patients strongly correlates to increasing levels of plasma neopterin, the oxidation product of 7,8-dihydroneopterin. Interferon-γ stimulation of macrophages causes the synthesis of 7,8-dihydroneopterin, a potent antioxidant that inhibits oxidative damage to cells,...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Mary Ann Liebert, INC
2010
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| Subjects: | |
| Online Access: | http://ir.unimas.my/id/eprint/2449/ http://ir.unimas.my/id/eprint/2449/1/Oxidant%20Production...pdf |